Restrictive cardiomyopathy with pseudotumor formation of the left ventricle
A 4-year-old girl had the insidious onset of congestive heart failure without apparent cause. Evaluation by echocardiography, thallous chloride Tl 201 scintigraphy, and angiography suggested the presence of either a neoplasm or restrictive cardiomyopathy with a localized mass effect on the left ventricle. Pathological specimens obtained by transvascular endomyocardial biopsy and at surgery defined the pathology to be restrictive cardiomyopathy. Analysis of myocardium by electron microscopy demonstrated a previously undescribed abnormality of the contractile elements involving the myofilaments and Z bands, with generalized secondary glycogen deposition.
Key wordsRestrictive cardiomyopathy Cardiac tumor Endomyocardial biopsy
Unable to display preview. Download preview PDF.
- 2.Chew CYC, Ziady GM, Raphael MJ, Nellen M, Oakley CM: Primary restrictive cardiomyopathy: Non-tropical endomyocardial fibrosis and hypereosinophilic heart disease.Br Heart J 39:399–413, 177Google Scholar
- 4.Evans RW, Raymond BA, Fox A, Nelson WP: The masquerades of primary myocardial disease: Case report.Milit Med 139:273–276, 1974Google Scholar
- 5.Fowler RS, Keith JD: Cardiac tumors, in Keith JD, Rowe RD, Vlad P (eds):Heart Disease in Infancy and Childhood. New York, Macmillan and Co, 1978, pp 1040–1047Google Scholar
- 6.Goodwin JF: Obliterative and restrictive cardiomyopathies, in Hurst JW (ed):The Heart. New York, McGraw-Hill Book Co Inc, 1978, pp 1580–1590Google Scholar
- 13.Lurie PR, Neustein HB: Endomyocardial biopsy in pediatrics, in Fenoglio JJ (ed):Endomyocardial Biopsy: Techniques and Applications. Boca Raton, Fla, CRC Press, 1982Google Scholar
- 14.Nabarro JDN: Cardiac involvement in malignant lymphoma.Arch Intern Med 92:258–264, 1963Google Scholar