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Electrical measurements in epithelial tissues: Theory and practice

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Abstract

The transport of ions from one side to the other of the continuous sheet of cells that constitutes an epithelium is most easily explored with the chambered preparation, in which the tissue is maintained between two bathing solutions of known composition. The chamber design must allow for the biological requirements of the tissue (such as oxygenation) as well as permit the electrical and/or chemical measurements desired. Methods for measuring electrical potential difference, short circuit current and tissue resistance are discussed, and consideration is given to the meaning of the numbers obtained in relation to the experimental procedure.

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Authors and Affiliations

  1. Department of Physiology School of Dentistry, University of Maryland, 21201, Baltimore, Maryland

    George W. Kidder III

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  1. George W. Kidder III
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Kidder, G.W. Electrical measurements in epithelial tissues: Theory and practice. J Biol Phys 1, 143–174 (1973). https://doi.org/10.1007/BF02308892

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