Skip to main content
SpringerLink
Log in

Probleme des «Biological Monitoring» von Benzolexpositionen

  • Beiträge
  • Published:
Sozial- und Präventivmedizin/Social and Preventive Medicine

Summary

The biological monitoring of workers exposed to benzene containing mixtures by phenol analysis in urine is complicated by the facts that varying amounts of phenolic compunds are also produced by other precursors than benzene and that coexposure with other chemicals can cause interactions in metabolism and elimination rates. In order to overcome these difficulties it is proposed

  1. a)

    to abandon the colorimetric methods and to use only gas chromatography as a standard and reference method,

  2. b)

    as an overall monitoring concept always to determine phenol pre-exposure values as well as the cresol and creatinine concentrations in urine, and to combine biological monitoring whenever possible with personal air sampling.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literatur

  1. Brewer, R., H., Weiskotten, H., G.; J. Med. Research35, 71 (1916)

    CAS  Google Scholar 

  2. Teisinger, J., Fiserova-Bergerova, V.; Arch. Mal. Profess.16, 221 (1955)

    CAS  Google Scholar 

  3. Int. Workshop on Toxicity of Benzene, Paris: 9th–11th Nov. 1976; Int. Arch. Occup. Environ. Hlth.41, 65–76 (1978)

  4. Berlin, M., Holm, S., Knutson, P., Tunek, A.; Arch. Toxicol. Suppl.2, 305–310 (1979)

    Article  Google Scholar 

  5. Angerer, J., Szadkowski, D., Manz, A. et al.; Int. Arch. Arbeitsmed.31, 1 (1973)

    Article  CAS  Google Scholar 

  6. Brief, R. S., Lynch, J., Bernath, T., Scala, R.A.; Am. Ind. Hyg. Assoc. J.41, 616–623 (1980)

    Article  CAS  Google Scholar 

  7. Lauwerys, R.; Scand. J. Work Environ. Hlth.1, 139–172 (1975)

    Article  CAS  Google Scholar 

  8. Fishbeck, W. A., Langer, R., R., Kociba, R., Y.; Am. Ind. Hyg. Assoc. J.36, 820 (1975)

    Article  CAS  Google Scholar 

  9. Eikmann, Th., Gabriel, M., Laenerts-Langanke, H., Prajsnar, D.; Zbl. Arbeitsmed.33, 40–48 (1983)

    CAS  Google Scholar 

  10. Kociba, R. J., Kalnins, R. V., Wade, C. E. et al.; Am. Ind. Hyg. Assoc. J.37, 183 (1976)

    Article  CAS  Google Scholar 

  11. Docter, H. J., Zielhuis, R. L.; Ann. Occup. Hyg.10, 317–326 (1967)

    CAS  PubMed  Google Scholar 

  12. Ikeda, M., Ohtsuji, H.; Tox. Appl. Pharmacol.20, 30, (1971)

    Article  CAS  Google Scholar 

  13. Ikeda, M., Ohtsuji, H., Imamura, T.; Xenobiotica2, 101 (1972)

    Article  CAS  Google Scholar 

  14. Demaurex, A., Küng, H.-L., Wirz, H.; Sozial- und Präventivmed,28, 88–94 (1983)

    CAS  Google Scholar 

  15. Yant, W., P., Schrenk, H., H.; J. Ind. Hyg. Toxicol.18, 69 (1936)

    CAS  Google Scholar 

  16. Theis, R., C., Benedict, S., R.; J. Biol. Chem.61, 67 (1924)

    CAS  Google Scholar 

  17. Buchwald, H.; Ann. Occup. Hyg.9, 7 (1966)

    CAS  PubMed  Google Scholar 

  18. Küng, H.-L., Larsen, M.; Arbeitsmed. Sozialmed. Arbeitshyg.4, 98 (1977)

    Google Scholar 

  19. Gibbs, H., D.; J. Biol. Chem.72, 649–664 (1927)

    CAS  Google Scholar 

  20. Bardodej, Z.; Arbeitsmed. Sozialmed. Arbeitshyg.3, 141–142 (1968)

    Google Scholar 

  21. Analysen in Biol. Material, Band 2, 7. Lieferung, Verlag Chemie, Weinheim, 1983

  22. Angerer, J., Lehnert, G.; Int. Arch. Occup. Environ. Hlth.43, 145–150 (1979)

    Article  CAS  Google Scholar 

  23. Dirmikis, S., M., Darbre, A.; J. Chromatog.94, 169–187 (1974)

    Article  CAS  Google Scholar 

  24. Buchet, J., P., Lauwerys, R.; J. Europ. Toxicol.1, 27 (1972)

    Google Scholar 

  25. Van Roosmalen, P., B., Purdham, J., Drummond, I.; Int. Arch. Occup. Environ. Hlth.48, 159–163 (1981)

    Article  Google Scholar 

  26. Angerer, J.; Int. Arch. Occup. Environ. Hlth.42. 257–268 (1979)

    Article  CAS  Google Scholar 

  27. Bauer, D.; 6. Int. Koll. für die Verhütung von Arbeitsunfällen und Berufskrankheiten in der chem. Industrie, Frankfurt, 18–20.6.1979, Int. Sektion der IVSS, Proceedings, 269–286, 1979

Download references

Author information

Authors and Affiliations

  1. c/o Abteilung Sicherheit und Umweltschutz, F. Hoffmann-La Roche & Co. AG, CH-4002, Basel

    D. Bauer

Authors
  1. D. Bauer
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bauer, D. Probleme des «Biological Monitoring» von Benzolexpositionen. Soz Präventivmed 29, 44–45 (1984). https://doi.org/10.1007/BF02301724

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02301724

Search

Navigation