Der Einfluß einiger antirheumatischer Substanzen auf Gewebsenzyme

Summary

Antirheumatic substances like adrenocorticotropin, acetylsalicylic acid, salicylic acid, phlorhizin and monoiodo acetic acid influence the metabolism. On the isolated cornea, they almost completely inhibit the reduction of triphenyltetrazolic chloride. Therefore they seem to disturb the glycolysis which is important for the development of the inflammation. In the concentration used, adrenocorticotropin influences the tissue without being dependent on the cortex of the adrenal gland. On the other hand the phlogistic “forapin” enhance the activity of dehydrases of the corneain situ.