Abstract
The aim of the present study was to develop a breath test to measure liquid gastric emptying rates that would be without radiation exposure and applicable to field testing. Four different test meals were investigated: a glucose meal, an amino acid meal, a fat meal, and a mixed meal (Ensure). The test meals were labeled with two markers, [13C]acetate and PEG-4000 (polyethylene glycol 4000). Gastric emptying rates were measured simultaneously by both breath test and the double-indicator technique in eight healthy male subjects. The appearance of13CO2 in the breath closely reflected gastric emptying of the four test meals as measured by the double-indicator technique. It is concluded that the [13C]acetate breath test is a reliable, noninvasive test to measure gastric emptying rates of liquid test meals.
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Mossi, S., Meyer-Wyss, B., Beglinger, C. et al. Gastric emptying of liquid meals measured noninvasively in humans with [13C]Acetate breath test. Digest Dis Sci 39 (Suppl 12), 107S–109S (1994). https://doi.org/10.1007/BF02300386
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DOI: https://doi.org/10.1007/BF02300386