Summary
Four Indonesian goats fedLeucaena leucocephala with a calcium to phosphorus ratio in excess of 6:1 for 472 days developed mandibular osteodystrophy fibrosa to varying degrees ranging from severe to slight. The animals appeared to grow normally but the animal with the most severe clinical symptoms lost weight for 35 days prior to the termination of the experiment. The other three animals either maintained or gained weight during this period. A balance study performed part way through the experiment revealed that the animal which subsequently lost weight was probably not storing calcium or phosphorus whereas the other animals had a positive calcium balance and were probably storing small amounts of phosphorus.
Histological examination of tissues taken after a post-mortem revealed that the kidney, parathyroid and thyroid glands and long bones were normal.
Résumé
Quatre chèvres indonésiennes nourries pendant 472 jours avecLeucaena leucocephala présentant un rapport phospho-calcique excessif de 6:1 ont développé, à des degrés divers, allant de léger à sévère, une dystrophie ostéofibreuse de la machoire. Leur croissance a semblé normale, mais la chèvre atteinte des symptômes les plus sévères a perdu du poids pendant 35 jours avant la fin de l'expérience. Les trois autres ont, soit conservé, soit accru leur poids pendant cette même période. Une recherche de bilan conduite séparément pendant la durée de l'étude a révélé que la chèvre qui avait perdu du poids au cours de l'essai n'avait probablement pas stocké le calcium ou le phosphore alors que les trois autres avaient un bilan positif en calcium et stockaient problement de petites quantités de phosphore. L'examen histologique des tissus prélevéspost-mortem a montré que le rein, les parathyroïdes, la thyroïde et les os longs présentaient un aspect normal.
Resumen
Cuatro cabras Indonesias alimentadas durante 472 días conLeucaena leucocefala, conuna relación de calcio y fósforo en exceso de 6.1, desarrollaron osteodistrófia fibrosa mandibular, la cual varió de severa amoderada. Los animales crecieron normalmente, pero uno de ellos, el cual presentó los síntomas más serveros, perdió peso por 35 días antes de terminar el experimento. Los tres animales restantes, mantuvieron o ganaron peso durante ese período. Todo parace indicar, que el animal que perdió peso, probablemente no estaba almacenando calcio o fósforo adecuadamente, mientras que los otros tres animales tuvieron un balance positivo de calcio y probablemente estaban almacenando pequeñas cantidades de fósforo. El examen microscópico de los tejidos colectados durante la necropsia, reveló que tanto los huesos largos como el riñón, tiroides y paratiroides estaban normales.
Similar content being viewed by others
References
Anon (1960). Formic Acid-Sodium Citrate Method.Manual of Histologic Staining Methods of the Armed Forces Institute of Pathology 3rd edn. McGraw-Hill Book Company, New York.
Andrews, A. H., Ingram, P. L. &Longstaffe, J. A. (1983).Veterinary Record,112, 404–406.
Groenwald, J. W., Thomas, A. D. &Du Toit, B. A. (1940).Onderstepoort Journal of Veterinary Science and Animal Industry,15, 299–309.
Jubb, K. V. F. &Kennedy, P. C. (1970). Osteodystrophia fibrosa.Pathology of Domestic Animals, Vol. 2. 2nd edn Academic Press, New York, pp. 35–38.
Murphy, W. J. B., McBarron, E. J. &Doyle, P. W. (1959).Australian Veterinary Journal,35, 524–529.
Obst, J. M., Chaniago, T. &Boyes, T. (1980). Survey of sheep and goats slaughtered at Bogor, West Java, Indonesia. Centre for Animal Research and Development, Bogor, Report No. 10.
Pellegrini, N., Gioli, G., Pozzo, F., Taccini, E., Renzoni, G. &Pambianco, L. A. (1980).Annali della Facolta de Medicina Veterinaria di Pisa,32, 271–282.
Sevilla, C. C. &Ternouth, J. H. (1980).Proceedings of the Australian Society of Animal Production,13, 449.
Walthall, J. C. &McKenzie, R. A. (1976).Australian Veterinary Journal,52, 11–16.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Yates, N.G., Hoffmann, D. & Seripto, S. Mandibular osteodystrophy fibrosa in indonesian goats fed leucaena. Trop Anim Health Prod 19, 121–126 (1987). https://doi.org/10.1007/BF02297330
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02297330