Pharmaceutisch weekblad

, Volume 1, Issue 1, pp 186–195 | Cite as

Isolation and identification of decomposition products of emetine

  • C. Schuijt
  • G. M. J. Beijersbergen van Henegouwen
  • K. W. Gerritsma
Original Articles

Abstract

On irradiation of emetine withUv-light, oxidation products are formed, whilst fragmentation of the emetine molecule also occurs. Under the influence of heat, only oxidation products of emetine are formed.

The identified products were found to account for 93% of the amount of thermochemically decomposed emetine, and for 102% in the case of photochemical decomposition. For both types of decomposition of emetine a scheme is presented.

Keywords

Emetine Mercuric Acetate Parent Peak Photochemical Decomposition Pharmaceutisch Weekblad Scientific Edition 

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Copyright information

© Bohn, Scheltema & Holkema 1979

Authors and Affiliations

  • C. Schuijt
    • 1
  • G. M. J. Beijersbergen van Henegouwen
    • 1
  • K. W. Gerritsma
    • 1
  1. 1.Department of Medicinal Chemistry, Subfaculty of PharmacyState University, Gorlaeus LaboratoriesLeidenThe Netherlands

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