, Volume 43, Issue 9–10, pp 537–545 | Cite as

Stability of mixed-ligand zinc(II) carboxylate complexes in thin-layer chromatography

  • A. Orinak
  • A. R. Timerbaev
  • R. Staskova
  • J. Vojtek
  • K. Ubik


The TLC stability of mixed-ligand zinc(II) carboxylate complexes (ZC) of the type Zn(RCOO)2L n , where L is caffeine, nicotinic acid, thiourea or phenazone (n=1 or 2), has been studied on silica gel and octadecyl-bonded silica layers. All the ZC examined were found to undergo partial decomposition during the chromatographic process when eluted both with non-aqueous and buffered mobile phases. According to off-line analyses performed by atomic absorption and mass spectrometry, the chromatographic stability of ZC was highly dependent on their molecular structure. The nature of organic base ligand has a dominant impact on stability, which increases in the order thiourea < phenazone < nicotinic acid < caffeine derivatives. The influence of the carboxylic ligand is of secondary importance and seems to be attributed to its steric properties.

Key Words

Thin-layer chromatography Zinc complexes Chromatographic stability Spectroscopic analysis 


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Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1996

Authors and Affiliations

  • A. Orinak
    • 1
  • A. R. Timerbaev
    • 2
  • R. Staskova
    • 3
  • J. Vojtek
    • 4
  • K. Ubik
    • 5
  1. 1.Department of Inorganic ChemistryP.J. Safarik UniversityKosiceSlovak Republic
  2. 2.Department of Analytical ChemistryJohannes Kepler UniversityLinzAustria
  3. 3.Department of Physical and Analytical ChemistryP.J. Safarik UniversityKosiceSlovak Republic
  4. 4.Laboratory of ContaminantsState Veterinary InstituteKosiceSlovak Republic
  5. 5.Institute of Organic Chemistry and BiochemistryAcademy of Science of the Czech RepublicPraha 6Czech Republic

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