Chemistry of Heterocyclic Compounds

, Volume 33, Issue 6, pp 698–702 | Cite as

Synthesis and mass spectroscopic investigation of some 6-(pyrazol-1-Yl)pyrimidines

  • G. G. Danagulyan
  • L. G. Saakyan
  • M. G. Zalinyan
  • P. B. Terent'ev
Article

Abstract

Condensation of 2-benzyl-4-hydrazino-6-methylpyrimidine with ethyl acetoacetate and its alkyl derivatives as well as with acetyl acetone, methyl methacrylate, and crotonaldehyde have given the corresponding 2-benzyl-4-methyl-6-(pyrazol-1-yl)pyrimidines which have been studied by PMR and mass spectrometry. Their biological activity has been investigated.

Keywords

Methyl Mass Spectrometry Ethyl Acetone Organic Chemistry 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    G. G. Danagulyan, L. G. Saakyan, P. B. Terent'ev, and M. G. Zalinyan, Arm. Khim. Zh.,44, 448 (1991).Google Scholar
  2. 2.
    G. G. Danagulyan, L. G. Saakyan, and M. G. Zalinyan, Khim. Geterotsikl. Soedin., No. 2, 225 (1992).Google Scholar
  3. 3.
    G. G. Danagulyan, L. G. Saakyan, G. A. Panosyan, G. A. Bulakhov, P. B. Terent'ev, and M. G. Zalinyan, Khim. Geterotsikl. Soedin., No. 11, 1545 (1993).Google Scholar
  4. 4.
    T. Akimoto, W. Tsukada, T. Yamasaki, H. Kojima, A. Kasahara, A. Akashi, K. Yamaguchi, and Y. Oshima, Nippon Yakurigaku Zasshi,65, No. 4, 378 (1969); Chem. Abstr.,73, 97256 (1970).Google Scholar
  5. 5.
    S. Asai, K. Nakagawa, and T. Hirayama, Jpn. Patent 7616681; Chem. Abstr.,85, 123961 (1976).Google Scholar
  6. 6.
    K. Shirakawa, Jpn. Patent 4492; Chem. Abstr.,61, 5666 (1964).Google Scholar
  7. 7.
    K. Shirakawa, Jpn. Patent 4493; Chem. Abstr.,61, 5666 (1964).Google Scholar
  8. 8.
    T. Nishimura, J. Miyamoto, and H. Fukuyasu, Yakugaku Zasshi,96, No. 3, 384 (1976); Chem. Abstr.,85, 355 (1976).Google Scholar
  9. 9.
    P. B. Terent'ev and A. P. Stankyavichus, Mass Spectrometric Analysis of Biologically Active Nitrogen Bases [in Russian], Mokslas, Vilnius (1987), p. 148.Google Scholar

Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • G. G. Danagulyan
  • L. G. Saakyan
  • M. G. Zalinyan
  • P. B. Terent'ev

There are no affiliations available

Personalised recommendations