Skip to main content
Log in

Reproducibility of the cardiovascular reactivity to a computerized version of the Stroop stress test in normotensive and hypertensive subjects

  • Research Paper
  • Published:
Clinical Autonomic Research Aims and scope Submit manuscript

Abstract

The 1-month reproducibility of haemodynamic and sympatho-adrenal responses to a standardized mental stress test was studied in ten normotensive and ten hypertensive individuals. The stress test was a computerized adaptation of the Stroop test and sympathetic activity was evaluated by measuring urinary catecholamine excretion. Three-way analysis of variance (stress, session, blood pressure) revealed significant increases in systolic and diastolic blood pressures and in heart rate during the stress test. Test-retest correlation coefficients for basal stress levels, and stress-induced variations were significant (r from 0.59 to 0.88). The stress test induced a significant increase in urinary noradrenaline excretion with large intra- and interindividual variability. The significant test-retest correlations and the lack of period effect for haemodynamic parameters indicated good temporal stability. However, a slight decrease in stress-induced reactivity was observed. This standardized mental stress test may be useful in epidemiological and therapeutic trials to measure blood pressure and heart rate responses, but measurement of urinary catecholamine excretion does not provide any additional information.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Conway J, Boon M, Jones JV, Sleight P. Neural and humoral mechanisms involved in blood pressure variability.J Hypertens 1984;2: 203–208.

    Google Scholar 

  2. Grillot M, Fauvel JP, Cottet-Emard JMet al. Spectral analysis of stress-induced change in blood pressure and heart rate in normotensive subjects.J Cardiovasc Pharmacol 1995;25: 448–452.

    Google Scholar 

  3. Mounier-Vebier C, Girard A, Consoli S, Laude D, Vacheron A, Elghozi JL. Cardiovascular reactivity to a new mental stress test: the maze test.Clin Autonom Res 1995;5: 145–150.

    Google Scholar 

  4. Pickering TG, Phil D, Gerin W. Ambulatory blood pressure monitoring and cardiovascular reactivity testing for the evaluation of the role of psychological factors and prognosis in hypertensive patients.Am Heart J 1988;116 (suppl. 5): 665–672.

    Google Scholar 

  5. Falkner B, Onesti G, Hamtra B. Stress response characteristics of adolescent with high genetic risk for essential hypertension: a five year's follow-up.Hypertension 1981;3: 583–591.

    Google Scholar 

  6. Von Eiff AW, Gogolin E, Jacobs U, Neus H. Heart rate reactivity under mental stress as a predictor of blood pressure development in children.J Hypertens 1985;3 (suppl. 4): S89-S91.

    Google Scholar 

  7. Light KC, Dolan CA, Davis MR, Sherwood A. Cardiovascular responses to an active coping challenge as predictors of blood pressure patterns 10 to 15 years latter.Psychosom Med 1992;54: 217–230.

    Google Scholar 

  8. Fredrikson M, Matthews KA. Cardiovascular response to behavioral stress and blood pressure variability in hypertension: a meta-analytic review.Ann Behav Med 1990;12: 30–39.

    Google Scholar 

  9. Light CK, Koepke JP, Obrist PA, Willis W. Psychological stress induces sodium and fluid retention in men at high risk for hypertension.Science 1983;220: 429–431.

    Google Scholar 

  10. Fauvel JP, Hadj-Aïssa A, Laville Met al. Stress induced renal functional alterations in normotensives.Am J Hypertens 1991;4: 955–958.

    Google Scholar 

  11. Cinciripini PM. Cognitive stress and cardiovascular reactivity. Relationship to atherosclerosis, arrythmias and cognitive control.Am Heart J 1986;112: 435–464.

    Google Scholar 

  12. Cacioppo JT. Social neuroscience: autonomic, neuroendocrine, and immune responses to stress.Psychophysiol. 1994;31: 11–16.

    Google Scholar 

  13. Steptoe A, Vögele C. Methodology of mental stress testing in cardiovascular research.Circulation 1991;83: II14-II24.

    Google Scholar 

  14. Widgren BR, Wikstrand J, Berglund G, Andersson OK. Increased response to physical and mental stress in men with hypertensive parents.Hypertension 1992;20: 606–611.

    Google Scholar 

  15. Sausen KP, Lovallo WR, Wilson MF. Heart rate reactivity, behavior pattern, and parental hypertension as predictors of cardiovascular activity during cognitive challenge.Psychophysiol 1991;28: 639–647.

    Google Scholar 

  16. MacDonald IA. How do we study autonomic function in humans?Fundam Clin Pharmacol 1995;9: 443–449.

    Google Scholar 

  17. Miller SB. Parasympathetic nervous system control of heart rate responses to stress in offspring of hypertensives.Psychophysiol 1994;31: 11–16.

    Google Scholar 

  18. Dimsdale JE, Ziegler MG. What do plasma and urinary cate-cholamines tell us about human response to stressors?Circulation 1991;83: II36-II42.

    Google Scholar 

  19. Lenders J, Houben H, Van Valderen R, Willemsen J, Thien T. Reproducibility of haemodynamic and plasma catecholamine responses to isometric exercise and mental arithmetic in normo-and hyper-tensive subjects.Clin Sci 1988;75: 615–619.

    Google Scholar 

  20. Langewitz W, Ruddel H, Noack H, Wachtarz K. The reliability of psychophysiological examinations under field conditions: results of repetitive mental stress testing in middle-aged men.Eur Heart J 1989;10: 657–665.

    Google Scholar 

  21. Fahrenberg J, Schneider HJ, Safian P. Psychophysiological assessments in a repeated-measurement design extending over a one-year interval: trends and stability.Biol Psychol 1987;24: 49–66.

    Google Scholar 

  22. Matthews KA, Rakaczky CJ, Stoney CM, Mannuck S.B. Are cardiovascular responses to behavioral stressors a stable individual difference variable in childhood?Psychophysiol 1987;24: 464–473.

    Google Scholar 

  23. Lovallo WR, Pincomb GA, Wilson MF. Heart rate reactivity and type A behavior as modifiers of physiological response to active and passive coping.Psychophysiol 1986;23: 105–112.

    Google Scholar 

  24. McKinney ME, Miner MH, Ruddel H,et al. The standardized mental stress test protocol: test-retest reliability and comparison with ambulatory blood pressure monitoring.Psychophysiol 1985;22: 453–463.

    Google Scholar 

  25. Foerster F. Psychophysiological response specificities: a replication over a 12-month period.Biol Psychol 1985;21: 169–182.

    Google Scholar 

  26. Carroll D, Turner JR, Lee HJ, Stephenson J. Temporal consistency of individual differences in cardiac response to a video game.Biol Psychol 1984;19: 81–93.

    Google Scholar 

  27. Arena JG, Blanchard EB, Andrasik F, Cotch PA, Myers PE. Reliability of psychophysiological assessment.Behav Res Ther 1983;21: 447–460.

    Google Scholar 

  28. Manuck SB, Schaefer DC. Stability of individual differences in cardiovascular reactivity.Physiol Behav 1978;21: 675–678.

    Google Scholar 

  29. Manuck SB, Garland FN. Stability of individual differences in cardiovascular reactivity: a thirteen month follow-up.Physiol Behav 1980;24: 621–624.

    Google Scholar 

  30. Freyschuss, U, Hjemdahl P, Juhlin-Dannfelt A, Linde B. Cardiovascular and sympathoadrenal responses to mental stress: influence of β-blockade.Am J Physiol 1988;255: H1443-H1451.

    Google Scholar 

  31. Jern S, Wall U, Bergbrant A. Long-term stability of blood pressure and pressor reactivity to mental stress in borderline hypertension.Am J Hypertens 1995;8: 20–28.

    Google Scholar 

  32. Tulen JHM, Mulder G, Pepplinkhuizen L, Man in't Veld AJ, Steenis HG, Moleman P. Effects of lorazepam on cardiac vagal tone during rest and mental stress: assessment by means of spectral analysis.Psychopharmacol 1991;114: 81–89.

    Google Scholar 

  33. Jern S, Pilhall M, Jern C, Carlsson SG. Short term reproducibility of a mental arithmetic stress test.Clin Sci 1991;81: 593–601.

    Google Scholar 

  34. Stroop JR. Studies of interference in serial verbal reaction.J Exp Physiol 1935;18: 643–662.

    Google Scholar 

  35. Fauvel JP, Bernard N, Hadj-Aïssa Aet al. Urinary catecholamines and methoxyamines during a psychological stress in subjects with different genetic risk of hypertension.Biogenic Amines 1991;3: 161–166.

    Google Scholar 

  36. Rodriguez C, Bernard N, Julien Cet al. Routine analysis of catecholamines and metabolites in urine by a liquid chromatographic column switching system.Intern J Environ Anal Chem 1986;25: 235–255.

    Google Scholar 

  37. Fauvel JP, Hadj-Aïssa A, Laville Met al. Cardiovascular reactivity to and renal impact of stress and exercise: effects of bisoprolol.J Cardiovasc Pharmacol 1990;16 (suppl. 5): S19-S24.

    Google Scholar 

  38. Fauvel JP, Laville M, Bernard Net al. Effects of lisinopril on stress-induced peak blood pressure and sodium excretion: a double-blind controlled study.J Cardiovasc Pharmacol 1994;23: 227–231.

    Google Scholar 

  39. Bland JM, Altman DG. Comparing methods of measurements: why plotting difference against standard method is missleading.Lancet 1995;346: 1085–1087.

    Google Scholar 

  40. Scraganian P, Hanley JA, Hollander BJet al. Exaggerated psychophysiological reactivity: issues in quantification and reliability.J Psychosom Res 1985;29: 393–405.

    Google Scholar 

  41. Girdler SS, Turner JR, Scherwood A, Light KC. Gender differences in blood pressure control during a variety of behavioral stressors.Psychosom Med 1990;52: 571–591.

    Google Scholar 

  42. McAdoo WG, Weinberger MH, Miller JZ, Fineberg NS, Grim CE. Race and gender influence hemodynamic responses to psychological and physical stimuli.J Hypertens 1990;8: 961–967.

    Google Scholar 

  43. Manhem K, Jern C, Pilhall M, Shanks G, Jern S. Hemodynamic response to psychosocial stress during menstrual cycle.Clin Sci 1991;81: 17–21.

    Google Scholar 

  44. Esler M. Renal catecholamine metabolism.Miner Electrolyte Metab 1989;15: 16–23.

    Google Scholar 

  45. Akerstedt T, Gillbreg M, Hjemdahl Pet al. Comparison of urinary and plasma catecholamines response to mental stress.Acta Physiol Scand 1983:117: 19–26.

    Google Scholar 

  46. Hjemdahl P, Freyschuss U, Juhlin-Dannfelt A, Linde B. Differentiated sympathetic activation during mental stress evoked by the Stroop test.Acta Physiol Scand 1984;527: 25–29.

    Google Scholar 

  47. Euler US. Quantification of stress by catecholamine analysis.Clin Pharmacol Ther 1964;5: 398–404.

    Google Scholar 

  48. Puybassel L, Lacolley P, Laurent Set al. Effects of clonidine on plasma catecholamines and neuropeptide Y in hypertensive patients at rest and during stress.J Cardiovasc Pharmacol 1993;21: 912–919.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fauvel, J.P., Bernard, N., Laville, M. et al. Reproducibility of the cardiovascular reactivity to a computerized version of the Stroop stress test in normotensive and hypertensive subjects. Clinical Autonomic Research 6, 219–224 (1996). https://doi.org/10.1007/BF02291137

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02291137

Keywords

Navigation