Summary
A cross-linked polystyrene resin with fixed ligands of the type (R)-N′, N′-dibenzyl-1,2-propanediamine in the form of a copper(II) complex displays high enantio-selectivity in ligand-exchange chromatography of amino acids. A microbore column (100 mm×1 mm i.d.) packed with angular particles of dp=5–10 μm generated up to 3500 theoretical plates, enabling a complete resolution of a mixture of three racemic amino acids into six components under isocratic conditions.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
V. A. Davankov, Yu. A. Zolotarev, A. A. Kurganov, J. Liquid Chromatogr.2, 1191 (1979).
V. A. Davankov inJ. C. Giddings, E. Grushka, eds., “Advances in Chromatography”, M. Dekker, Inc., New York, N.Y. 1980; Vol. 18, pp. 139–195.
S. V. Rogozhin, V. A. Davankov, Ger. Pat. No. 1932190; C.A. 72, 90875C (1970).
K. Bernauer, Swiss Pat. No. 509239; C.A. 76, 60602 (1972).
V. A. Davankov, Yu. A. Zolotarev, J. Chromatogr.155, 285, 295, 303 (1978).
B. Lefebvre, R. Audebert, C. Quivoron, J. Liquid Chromatogr.1, 761 (1978).
G. Gübitz, W. Jellenz, G. Löfler, W. Santi, J. High Res. Chromatogr./Chromatogr. Commun.2, 145 (1979).
A. Foucault, M. Caude, L. Oliveross, J. Chromatogr.185, 345 (1979).
V. A. Davankov, S. V. Rogozhin, J. Chromatogr.60, 280 (1971).
J. N. LePage, W. Lindner, G. Davies, D. E. Seitz, B. L. Karger, Anal. Chem.51, 433 (1979).
W. Lindner, J. N. LePage, G. Davies, D. E. Seitz, B. L. Karger, J. Chromatogr.185, 323 (1979).
J. Gaal, J. Inczédy, Talanta23, 78 (1976).
P. E. Hare, E. Gil-Av, Science204, 1226 (1979).
A. A. Kurganov, L. Ya. Zhuchkova, V. A. Davankov, Makromol. Chem.180, 2101 (1979).
Author information
Authors and Affiliations
Additional information
12th publication in the series dealing with the ligand-exchange chromatography of racemates. Previous publications: ref. [1].
Rights and permissions
About this article
Cite this article
Davankov, V.A., Kurganov, A.A. High-performance liquid chromatography ofα-amino acids on a polystyrene resin with fixed ligands of the type (R)-N′, N′-dibenzyl-1,2-propanediamine. Chromatographia 13, 339–341 (1980). https://doi.org/10.1007/BF02290901
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02290901