Chemistry of Heterocyclic Compounds

, Volume 34, Issue 1, pp 111–114 | Cite as

Basicity of 3,6-diphenyl-1,2,4,5-tetrazine

  • R. E. Trifonov
  • V. Yu. Zubarev
  • A. A. Malin
  • V. A. Ostrovskii


We have determined the basicity of 3,6-diphenyl-1,2,4,5-tetrazine in aqueous solutions of sulfuric acid (pKBH+ is −4.8). According to quantum chemical calculations done by the MNDO method and theab initio method in a 6-31G++ basis, the tetrazine ring is a nonpolar, highly aromatic system similar to benzene. The aromaticity of the tetrazine hererocycle decreases significantly upon protonation, which considerably destabilizes the protonated form.


Aqueous Solution Benzene Organic Chemistry Sulfuric Acid Chemical Calculation 
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Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • R. E. Trifonov
  • V. Yu. Zubarev
  • A. A. Malin
  • V. A. Ostrovskii

There are no affiliations available

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