Skip to main content
SpringerLink
Log in

Analysis of diisocyanate monomers in chemical products containing polyurethanes by high pressure liquid chromatography

  • Originals
  • Published:
Chromatographia Aims and scope Submit manuscript

Summary

High pressure liquid chromatographic methods for the determination of diphenylmethane-4,4′-diisocyanate (MDI) and toluene diisocyanate (TDI) in chemical products are described. The MDI- and TDI monomers were determined as their urea derivative formed by the reaction with 9-(methyl aminomethyl)-anthracene. Using these methods MDI- and TDI monomer concentrations have been determined in 55 chemical products: sealing waxes, insulating- and adhesive foam, hardener, primer, adhesives and surface coatings. The recovery of both MDI and TDI monomers from various types of chemical product was found to be 92–97%, and the relative standard deviations of the methods was <5% for all types of products.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. F. W. Bilmeyer, Textbook of polymer Chemistry, Interscience Publishers Inc., New York, 1957, p. 407.

    Google Scholar 

  2. NIOSH Information Profiles on Potential Occupational Hazards (PB-276 678), US Department of Commerce, National Technical Information Service, Rockville MD, 1977, p. 265.

  3. NIOSH Criteria for a Recommended Standard: Occupational Exposure to Diisocyanate (PB-75-215), US Department of Health, Education, Welfare, Public Health Service, Center for Disease Control, Rockville MD, 1977.

  4. P. Dupart, B. Gradski, B. Marignac, J. Eur. Toxicol9, 41 (1976).

    Google Scholar 

  5. H. H. Karol, H. H. Ioset, Y. C. Alaire, Am. Ind. Hyg. Assoc. J.39, 454 (1978).

    Google Scholar 

  6. C. Cavelier, P. Mereau, J. M. Mur, A. Cicolella, Ann. Occup. Hyg.21, 121 (1978).

    Google Scholar 

  7. C. Sangö, E. Zimmerson, J. Liquid Chromatogr.3, 971 (1980).

    Google Scholar 

  8. K. Andersen, A. Gudehn, J.-O. Levin, C.-A. Nilsson, Chemosphere11, 3 (1982).

    Google Scholar 

  9. R. G. Melcher, Anal. Chem.55, 40 (1983).

    Google Scholar 

  10. C. J. Purnell, R. F. Walker, Analyst110, 893 (1985).

    Google Scholar 

  11. P. McFadyen, J. Chromatogr.123, 468 (1976).

    Google Scholar 

  12. G. Cox, K. Sugden, Anal. Chim. Acta.91, 365 (1977).

    Google Scholar 

  13. D. A. Bagon, H. L. Hardy, J. Chromatogr.152, 560 (1978).

    Google Scholar 

  14. M. Furukawa, T. Yokoyman, J. Chromatogr.198, 212 (1980).

    Google Scholar 

  15. D. J. H. Edwards, J. High Resolut. Chromatogr./Chromatogr. Commun.3, 190 (1980).

    Google Scholar 

  16. R. F. Walker, P. A. Ellwood, H. L. Hardy, P. A. Goldberg, J. Chromatogr.301, 485 (1984).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. National Environmental Research Institute, Ministry of Environment, Mørkhøj Bygade 26 H, DK-2860, Søborg, Denmark

    S. C. Rastogi

Authors
  1. S. C. Rastogi
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rastogi, S.C. Analysis of diisocyanate monomers in chemical products containing polyurethanes by high pressure liquid chromatography. Chromatographia 28, 15–18 (1989). https://doi.org/10.1007/BF02290375

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02290375

Key Words

Search

Navigation