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Repopulation of thymus, spleen and bone-marrow of irradiated AKR mice injected with normal or irradiated bone-marrow cells

Experientia volume 27, pages 1212–1214 (1971)Cite this article

Résumé

L'utilisation d'une race de souris (AKR/T1Ald) ne possédant que 38 chromosomes a permis de montrer que les cellules de moelle que l'on injecte à un individu irradié repeuplent directement la moelle, le thymus et la rate du receveur. Si le donneur est irradié, la pénétration des cellules n'est importante que dans la rate du receveur.

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References

  1. H. S. Micklem, C. M. Clarke, E. P. Evans andC. E. Ford, Transplantation6, 299 (1968).

    Google Scholar 

  2. C. E. Ford, H. S. Micklem, E. P. Evans, J. G. Gray andD. A. Ogden, Ann. N.Y. Acad. Sci.129, 283 (1966).

    Google Scholar 

  3. H. S. Micklem andD. A. Ogden, IVth Int. Congr. Radiation Res., Abstr. 565 (1970).

  4. D. W. H. Barnes, G. Breckon, C. E. Ford, H. S. Micklem andD. A. Ogden,The Lymphocyte in Immunology and Haemopoiesis (Ed.J. M. Yoffrey; Arnold, London 1967), p. 207.

    Google Scholar 

  5. C. E. Ford, J. L. Hamerton, D. W. H. Barnes andJ. F. Loutit, Nature, Lond.177, 452 (1956).

    Google Scholar 

  6. H. S. Micklem andC. E. Ford, Transplant. Bull.26, 436 (1960).

    Google Scholar 

  7. H. S. Micklem, C. E. Ford, E. P. Evans andJ. G. Gray, Proc. R. Soc. B.165, 78 (1966).

    Google Scholar 

  8. A. Takada, Y. Takada, C. C. Huang andJ. L. Ambrus, J. exp. Med.129, 445 (1969).

    Google Scholar 

  9. A. Léonard andGh. Deknudt, Experientia22, 715 (1966).

    Google Scholar 

  10. A. Léonard andGh. Deknudt, Nature, Lond.214, 504 (1967).

    Google Scholar 

  11. A. Léonard andGh. Dekundt, IAEA, SM-118/27, 305 (1969).

    Google Scholar 

  12. A. Sassen, personal communication.

  13. J. E. Till andE. A. McCulloch, Radiation Res.14, 213 (1961).

    Google Scholar 

  14. J. E. Till andE. A. McCulloch, Radiation18, 96 (1963).

    Google Scholar 

  15. L. G. Lajtha,Current Topics in Radiation Research p. 139 (Ed.M. Ebert andA. Howard; North Holland Publisher Co., Amsterdam 1965, vol. 1, p. 139.

    Google Scholar 

  16. S. Hellman andH. E. Grate, IAEA, SM-103/4, 187 (1968).

    Google Scholar 

  17. H. Blomgren, Expl. Cell Res.58, 353 (1969).

    Google Scholar 

  18. D. B. Thomas andC. C. Congdon, J. Physiol., Lond.188, 28P (1967).

  19. J. F. Duplan, C. r. Soc. Biol., Paris159, 1277 (1965).

    Google Scholar 

  20. E. Legrand andJ. F. Duplan, C. r. Acad. Sci., Paris268, 2990 (1969).

    Google Scholar 

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Authors and Affiliations

  1. Department of Radiobiology, Centre d'Etude de l'Energie Nucléaire, C.E.N./S.C.K., B-2400, Mol, Belgium

    A. Léonard, A. Declève & J. R. Maisin

Authors
  1. A. Léonard
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  2. A. Declève
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  3. J. R. Maisin
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Acknowledgements. This work was supported by grants from the ‘Fonds de la Recherche scientifique fondamentale collective’. The helpful assistance of Mr.G. Linden andG. Mattelin is gratefully acknowledged.

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Léonard, A., Declève, A. & Maisin, J.R. Repopulation of thymus, spleen and bone-marrow of irradiated AKR mice injected with normal or irradiated bone-marrow cells. Experientia 27, 1212–1214 (1971). https://doi.org/10.1007/BF02286936

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