The American Journal of Digestive Diseases

, Volume 6, Issue 3, pp 269–277 | Cite as

Needle biopsy of the liver

  • Charles H. Brown
Current Gastroenterology


The value of liver biopsy depends first, on adequate tissue for the pathologist to examine and second, on the astuteness of the pathologist. Minor changes in the microscopic picture can make a great difference in the diagnosis. The value of our biopsies has increased as our pathologists have had more experience with them. A pathologist experienced in interpretation of specimens of needle biopsies of the liver is essential to successful diagnosis.

Using the subcostal approach in patients with palpable livers, and the thoracic or intracostal approach in those whose livers were not experienced in interpretation of specimens of needle biopsies of the liver is essential to successful diagnosis.


Public Health Liver Biopsy Needle Biopsy Microscopic Picture Adequate Tissue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Paul B. Hoeber, Inc., Medical Division of Harper & Brothers 1961

Authors and Affiliations

  • Charles H. Brown
    • 1
  1. 1.From the Department of GastroenterologyThe Cleveland Clinic Foundation, and The Frank E. Bunts Educational InstituteCleveland

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