Abstract
This study was designed to examine the clinical significance and the reliability of hemifield pattern reversal VEPs in the assessment of homonymous visual field defects due to retrochiasmal lesions.
13 patients with traumatic, neoplastic or ischemic lesions of the cerebral parenchyma, and 18 normal subjects were studied.
The results show that amplitude asymmetries over 4 μV (between responses evoked by right and left hemifield stimulation, recorded ipsilaterally to the stimulated hemifield) are clinically relevant for hemianopic visual field defect.
Significant correlations were found between the VEP features and the site of the damage: lesions of the occipital cortex were generally found to cause more pronounced bioelectrical abnormalities than those due to lesions affecting the visual pathways, with cortical sparing.
Sommario
Viene discussa la utilità clinica dello studio dei PVE da “pattern-reversal” nella diagnosi dei difetti campimetrici emianopsici omonimi da lesioni retrochiasmatiche (documentate dalla TAC).
Sono stati studiati 13 pazienti affetti da lesioni cerebrali di natura traumatica, neoplastica o ischemica, e 18 soggetti normali.
Dai risultati si deduce che asimmetrie di ampiezza superiori a 4 μV, tra le risposte evocate per stimolazione dei singoli emicampi destro e sinistro (registrate da elettrodi posti omolateralmente all'emicampo stimolato), sono clinicamente suggestive della presenza di emianopsia omonima.
Sono emerse, inoltre, correlazioni tra quadro bioelettrico ed anatomo-lesionale: le lesioni della corteccia occipitale provocano, generalmente, anomalie bioelettriche più evidenti rispetto a quelle dovute a lesioni interessanti le vie ottiche con risparmio della corteccia stessa.
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Maccolini, E., Andreoli, A., Valdé, G. et al. Hemifield pattern-reversal visual evoked potentials (VEPs) in retrochiasmal lesions with homonymous visual field defect. Ital J Neuro Sci 7, 437–442 (1986). https://doi.org/10.1007/BF02283022
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DOI: https://doi.org/10.1007/BF02283022