Abstract
Characteristics of the M-cholinoblocking activities of the alkaloid imperialine, three of its chlorine derivatives, and atropine have been shown. α-Chloroimperialine is a highly active central mixed M2,4-cholinoblocker, while its β-isomer is predominantly a peripheral mixed M2,4-cholinoblocker; a mixture of the α- and β-isomers is a central selective, and imperialine a peripheral selective, M2-cholinoblocker.
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Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 40 64 75. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 613–616, July–August, 1997.
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Mirzaev, Y.R., Shakirov, R. & Shakirova, U.T. Structure and M-cholinoblocking activity of chlorine derivatives of imperialine. Chem Nat Compd 33, 473–475 (1997). https://doi.org/10.1007/BF02282368
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DOI: https://doi.org/10.1007/BF02282368