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Assignment of the human ST2 gene to chromosome 2 at q11.2

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Abstract

The humanSt2 locus has been assigned to chromosome 2, using a human ST2 cDNA clone, by a human/rodent somatic cell hybrid mapping panel. TheSt2 locus has also been mapped to chromosome 2811.2, using a human ST2 genomic DNA clone, by in situ hybridization. The locus is very tightly linked to theIl-1r1 locus. Together with the structural similarity of ST2 to IL-1RI, these data suggest functional relationships between these two genes.

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References

  • Feinberg AP, Vogelstein B (1983) A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132:6–13

    Google Scholar 

  • Inazawa J, Saito H, Ariyama T, Abe T, Nakamura Y (1993) High-resolution cytogenetic mapping of 342 new cosmid markers including 43 RFLP markers on human chromosome 17 by fluorescence in situ hybridization. Genomics 17:153–162

    Google Scholar 

  • Tominaga S (1989) A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor. FEBS Lett 258: 301–304

    Google Scholar 

  • Tominaga S, Jenkins NA, Gilbert DJ, Copeland NG, Tetsuka T (1991) Molecular cloning of the murine ST2 gene. Characterization and chromosomal mapping. Biochim Biophys Acta 1090: 1–8

    Google Scholar 

  • Tominaga S, Yokota T, Yanagisawa K, Tsukamoto T, Takagi T, Tetsuka T (1992) Nucleotide sequence of a complementary DNA for human ST2. Biochim Biophys Acta 1171:215–218

    Google Scholar 

  • Wahl GM, Stern M, StarkGR (1979) Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethylpaper and rapid hybridization by using dextran sulfate. Proc Natl Acad Sci USA 76:3683–3687

    Google Scholar 

  • Williamson R, Bowcock A, Kidd K, Pearson P, Schmidtke J, Ceverha P, Chipperfield M, Cooper DN, Coutelle C, Hewitt J, Klinger K, Langley K, Beckmann J, Tolley M, Maidak B (1991) Report of the DNA committee and catalogues of cloned and mapped genes, markers formatted for PCR and DNA polymorphisms. Cytogenet Cell Genet 58:1190–1832

    Google Scholar 

  • Yanagisawa K, Takagi T, Tsukamoto T, Tetsuka T, Tominaga S (1993) Presence of a novel primary response gene ST2L, encoding a product highly similar to the interleukin 1 receptor type I. FEBS Lett 318:83–87

    Google Scholar 

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Authors and Affiliations

  1. Department of Biochemistry II, Jichi Medical School, 3311-1 Yakushiji, Minamikawachi-machi, 329-04, Kawachi-gun, Tochigi, Japan

    Shin-ichi Tominaga

  2. Department of Hygiene, Hematology and Oncology Unit, Kyoto Prefectural University of Medicine, Kamigyo-ku, 602, Kyoto, Japan

    Johji Inazawa

  3. Department of Neurology, Brain Research Institute, Niigata University, 951, Niigata, Japan

    Shoji Tsuji

Authors
  1. Shin-ichi Tominaga
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  2. Johji Inazawa
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  3. Shoji Tsuji
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Tominaga, Si., Inazawa, J. & Tsuji, S. Assignment of the human ST2 gene to chromosome 2 at q11.2. Hum Genet 97, 561–563 (1996). https://doi.org/10.1007/BF02281860

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  • DOI: https://doi.org/10.1007/BF02281860

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