Abstract
A new methane plasma polymer was used to treat eight polymethylmetacrylate intraocular lenses (IOL). Another group of four lenses which had no treatment was used as control. The groups were compared in terms of the amount of endothelial cell damage caused after each of the twelve IOLs touched the central endothelium of 12 separate New Zealand rabbit corneas for 30 secondsin vitro. The amount of damage was estimated by means of vital staining with nitroblue tetrazolium and scanning electron microscopy. We found that the untreated (control) group of IOL produced significantly more endothelial cell damage in comparison with the treated groups. Further studies are needed to evaluate the clinical significance of our findings.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Bourne WM, Kaufman HE. Endothelial damage associated with intraocular lenses. Am J Ophthalmol 1976; 81: 482–5.
Forstot SL, Blackwell WL, Jaffe NS, Kaufman HE. Effect of intraocular lens implantation on the corneal endothelium. Trans Am Acad Ophthalmol Otolaryngol 1977; 83: 195–203.
Kaufman HE, Katz JI. Endothelial damage from intraocular lens insertion. Invest Ophthalmol 1976; 15: 996–1000.
Kaufman HE, Katz JI, Valenti J, Sheets JW, et al. Corneal endothelium damage with intraocular lenses: Contact adhesion between surgical materials and tissue. Science 1977; 198: 525–7.
Katz JI, Kaufman HE, Goldberg EP, Sheets JW. Prevention of endothelial cell damage from intraocular lens insertion. Trans Am Acad Ophthalmol Otolaryngol 1977; 83: 204–11.
Kaufman HE, Katz JI. Effect of intraocular lenses on the corneal endothelium. Trans Ophthalmol Soc UK 1977; 97: 265–7.
Sugar J, Mitchelson J, Kraff M. Endothelial trauma and cell loss from intraocular lens insertion. Arch Ophthalmol 1978; 96: 449–50.
Olson RJ, Slappey TE. Corneal endothelial damage induced by intraocular lens: Anin vitro study. Am Intraocular Implant Soc J 1979; V: 321–3.
Olson RJ, Kolodner H, Morgan KS, Escapini H Jr., et al. Polyvinyl alcohol as a protective coating on intraocular lenses. Arch Ophthalmol 1980; 98: 1840–2.
Koziol JE, Peyman GA, Yasuda H. Evaluation of a new silicone-methane polymer contact lens. Arch Ophthalmol 1983; 101: 1779–81.
Yasuda H. Plasma modification of polymers. J Macromol Sci Chem 1976; 3: 383–420.
Yasuda H, Shorma AK, Yasuda T. Effect of orientation and mobility of polymer molecule at surfaces on contact angle and its hysteresis. J Polymer Sci: Polymer Phy Ed 1981; 19: 1205–91.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Badaro, R.M., Koziol, J.E. & Peyman, G.A. Methane plasma as a protective coating on intraocular lenses: An in vitro study. Int Ophthalmol 13, 357–360 (1989). https://doi.org/10.1007/BF02279873
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02279873