International Ophthalmology

, Volume 13, Issue 5, pp 357–360 | Cite as

Methane plasma as a protective coating on intraocular lenses: An in vitro study

  • R. M. Badaro
  • J. E. Koziol
  • G. A. Peyman


A new methane plasma polymer was used to treat eight polymethylmetacrylate intraocular lenses (IOL). Another group of four lenses which had no treatment was used as control. The groups were compared in terms of the amount of endothelial cell damage caused after each of the twelve IOLs touched the central endothelium of 12 separate New Zealand rabbit corneas for 30 secondsin vitro. The amount of damage was estimated by means of vital staining with nitroblue tetrazolium and scanning electron microscopy. We found that the untreated (control) group of IOL produced significantly more endothelial cell damage in comparison with the treated groups. Further studies are needed to evaluate the clinical significance of our findings.

Key words

cataract surgery corneal endothelium endothelial cell loss intraocular lens coating methane plasma polymer 


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  1. 1.
    Bourne WM, Kaufman HE. Endothelial damage associated with intraocular lenses. Am J Ophthalmol 1976; 81: 482–5.PubMedGoogle Scholar
  2. 2.
    Forstot SL, Blackwell WL, Jaffe NS, Kaufman HE. Effect of intraocular lens implantation on the corneal endothelium. Trans Am Acad Ophthalmol Otolaryngol 1977; 83: 195–203.Google Scholar
  3. 3.
    Kaufman HE, Katz JI. Endothelial damage from intraocular lens insertion. Invest Ophthalmol 1976; 15: 996–1000.PubMedGoogle Scholar
  4. 4.
    Kaufman HE, Katz JI, Valenti J, Sheets JW, et al. Corneal endothelium damage with intraocular lenses: Contact adhesion between surgical materials and tissue. Science 1977; 198: 525–7.PubMedGoogle Scholar
  5. 5.
    Katz JI, Kaufman HE, Goldberg EP, Sheets JW. Prevention of endothelial cell damage from intraocular lens insertion. Trans Am Acad Ophthalmol Otolaryngol 1977; 83: 204–11.Google Scholar
  6. 6.
    Kaufman HE, Katz JI. Effect of intraocular lenses on the corneal endothelium. Trans Ophthalmol Soc UK 1977; 97: 265–7.PubMedGoogle Scholar
  7. 7.
    Sugar J, Mitchelson J, Kraff M. Endothelial trauma and cell loss from intraocular lens insertion. Arch Ophthalmol 1978; 96: 449–50.PubMedGoogle Scholar
  8. 8.
    Olson RJ, Slappey TE. Corneal endothelial damage induced by intraocular lens: Anin vitro study. Am Intraocular Implant Soc J 1979; V: 321–3.Google Scholar
  9. 9.
    Olson RJ, Kolodner H, Morgan KS, Escapini H Jr., et al. Polyvinyl alcohol as a protective coating on intraocular lenses. Arch Ophthalmol 1980; 98: 1840–2.PubMedGoogle Scholar
  10. 10.
    Koziol JE, Peyman GA, Yasuda H. Evaluation of a new silicone-methane polymer contact lens. Arch Ophthalmol 1983; 101: 1779–81.PubMedGoogle Scholar
  11. 11.
    Yasuda H. Plasma modification of polymers. J Macromol Sci Chem 1976; 3: 383–420.Google Scholar
  12. 12.
    Yasuda H, Shorma AK, Yasuda T. Effect of orientation and mobility of polymer molecule at surfaces on contact angle and its hysteresis. J Polymer Sci: Polymer Phy Ed 1981; 19: 1205–91.Google Scholar

Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • R. M. Badaro
    • 1
  • J. E. Koziol
    • 2
  • G. A. Peyman
    • 1
  1. 1.The Lions Eye Research Laboratories, LSU Eye CenterLouisiana State University Medical Center School of MedicineNew OrleansUSA
  2. 2.the offices of Dr. KoziolArlington HeightsUSA

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