Methane plasma as a protective coating on intraocular lenses: An in vitro study
- 24 Downloads
A new methane plasma polymer was used to treat eight polymethylmetacrylate intraocular lenses (IOL). Another group of four lenses which had no treatment was used as control. The groups were compared in terms of the amount of endothelial cell damage caused after each of the twelve IOLs touched the central endothelium of 12 separate New Zealand rabbit corneas for 30 secondsin vitro. The amount of damage was estimated by means of vital staining with nitroblue tetrazolium and scanning electron microscopy. We found that the untreated (control) group of IOL produced significantly more endothelial cell damage in comparison with the treated groups. Further studies are needed to evaluate the clinical significance of our findings.
Key wordscataract surgery corneal endothelium endothelial cell loss intraocular lens coating methane plasma polymer
Unable to display preview. Download preview PDF.
- 2.Forstot SL, Blackwell WL, Jaffe NS, Kaufman HE. Effect of intraocular lens implantation on the corneal endothelium. Trans Am Acad Ophthalmol Otolaryngol 1977; 83: 195–203.Google Scholar
- 5.Katz JI, Kaufman HE, Goldberg EP, Sheets JW. Prevention of endothelial cell damage from intraocular lens insertion. Trans Am Acad Ophthalmol Otolaryngol 1977; 83: 204–11.Google Scholar
- 8.Olson RJ, Slappey TE. Corneal endothelial damage induced by intraocular lens: Anin vitro study. Am Intraocular Implant Soc J 1979; V: 321–3.Google Scholar
- 11.Yasuda H. Plasma modification of polymers. J Macromol Sci Chem 1976; 3: 383–420.Google Scholar
- 12.Yasuda H, Shorma AK, Yasuda T. Effect of orientation and mobility of polymer molecule at surfaces on contact angle and its hysteresis. J Polymer Sci: Polymer Phy Ed 1981; 19: 1205–91.Google Scholar