Summary
An automated on-line sampling and analytical set-up for the control of fermentations was studied incorporating a microdialysis probe as the sampling device. Applications to a penicillin broth and an ethanol fermentation were studied. Typical recovery values of carbohydrates were found to be close to 100% even after exposure of the microdialysis probe in the process for about 30 h.
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Marko-Varga, G., Buttler, T., Gorton, L. et al. A study of the use of microdialysis probes as a sampling unit in on-line bioprocess monitoring in conjunction with column liquid chromatography. Chromatographia 35, 285–289 (1993). https://doi.org/10.1007/BF02277511
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DOI: https://doi.org/10.1007/BF02277511