, Volume 33, Issue 7–8, pp 336–338 | Cite as

Chiral ligand exchange chromatography on polygalactomannan (Guaran)

  • R. Mathur
  • S. Bohra
  • V. Mathur
  • C. K. Narang
  • N. K. Mathur


The Chiral discriminating properties of the legume seed (Cyamopsis tetragonalobus) polysaccharide, guaran, has been investigated by this laboratory. Due to the presence of cis-hydroxyl groups in its molecule, guaran a galactomannan, forms tetracoordinated polymeric complexes with boron, resulting in cross-linking and gelling. Ligand exchange between the polymeric boron complex and a low molecular weight chiral diol can take place with stereoselectivity. The principle has been applied for the resolution of (±) mandelic acid by using ligand exchange chromatography.

Key Words

Column liquid chromatography Chiral discrimination Guaran-borate complex Mandelic acid enantiomers 


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Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1992

Authors and Affiliations

  • R. Mathur
    • 1
  • S. Bohra
    • 1
  • V. Mathur
    • 1
  • C. K. Narang
    • 1
  • N. K. Mathur
    • 1
  1. 1.Department of ChemistryUniversity of JodhpurJodhpurIndia

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