Chromatographia

, Volume 33, Issue 7–8, pp 336–338 | Cite as

Chiral ligand exchange chromatography on polygalactomannan (Guaran)

  • R. Mathur
  • S. Bohra
  • V. Mathur
  • C. K. Narang
  • N. K. Mathur
Originals

Summary

The Chiral discriminating properties of the legume seed (Cyamopsis tetragonalobus) polysaccharide, guaran, has been investigated by this laboratory. Due to the presence of cis-hydroxyl groups in its molecule, guaran a galactomannan, forms tetracoordinated polymeric complexes with boron, resulting in cross-linking and gelling. Ligand exchange between the polymeric boron complex and a low molecular weight chiral diol can take place with stereoselectivity. The principle has been applied for the resolution of (±) mandelic acid by using ligand exchange chromatography.

Key Words

Column liquid chromatography Chiral discrimination Guaran-borate complex Mandelic acid enantiomers 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. [1]
    S. G. Allenmark, Chromatographic Enantioseparation: Methods and applications, Ellis Horwood Ltd., Chichester 1988.Google Scholar
  2. [2]
    S. V. Rogozhin, V. A. Davankov, Dokl. Akad. Mank USSR,192, 1288 (1970).Google Scholar
  3. [3](a)
    V. A. Davankov, V. A. Zolotarev, J. Chromatogr155, 285 (1978).Google Scholar
  4. [3](b)
    S. V. Rogozhin, V. A. Davankov, Chem., Commun., 490 (1971).Google Scholar
  5. [3](c)
    B. Lefebvre, R. Audebert, C. Quivoron, J. Liquid Chromatogr.1, 761 (1978).Google Scholar
  6. [3](d)
    G. Gübitz, W. Jellenz, W. Santi, J. Liquid Chromatogr.4, 701 (1981).Google Scholar
  7. [4]
    H. Steinberg, Organoboron Chemistry, Vol. 1, John Wiley & Sons, Inc., New York, 626 (1964).Google Scholar
  8. [5](a)
    R. F. Nickerson, J. Inorg. Nucl. Chem.32 1400 (1970)Google Scholar
  9. [5](b)
    K. Yoshino, M. Kotaka, M. Okamoto, H. Kakihana, Bull Chem Soc. Jpn.52, 3005 (1979).Google Scholar
  10. [5](c)
    M. Vanduin, J. A. Peters, A. P. G. Kieboom, Van Bekkum, Tetrahedron.1411 (1985).Google Scholar
  11. [6]
    R. L. Whistler, Industrial Gums, 2nd Ed., Academic Press, New York (1973).Google Scholar
  12. [7]
    R. Mathur, S. Bohra, C. K. Narang, N. K. Mathur, J. Liq. Chromatogr. (Accepted for publication).Google Scholar

Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1992

Authors and Affiliations

  • R. Mathur
    • 1
  • S. Bohra
    • 1
  • V. Mathur
    • 1
  • C. K. Narang
    • 1
  • N. K. Mathur
    • 1
  1. 1.Department of ChemistryUniversity of JodhpurJodhpurIndia

Personalised recommendations