Summary
A modified gas chromatographic method is described for the determination of free monomer in contact lenses, irrespective of the method of production. It thus becomes possible to assess very quickly the conformity of such lenses with hygiene regulations. This method allows direct supervision of production or determination of the quality of a product of unknown origin in only 15 min. Production tests of new polymerization initiators, reactors for polymerization, etc. can also be carried out.
References
U.S. Pat. No. 3728317 (1973).
U.S. Pat. No. 4123408 (1978).
U.S. Pat. No. 3808179 (1974).
E. Malten, R. Wigwers, J. A. C. J.5, 178 (1979).
H. Proctor, J. Hughes, Chemical Hazards of the Workplace, 239 Philadelphia, 1978, p. 89.
A Guide to Health and Safety in GRP-Fabrication, Executive HMSO Publ. Centre, London, 1987, p. 79.
W. Arens, C. Siegert, Gas und Wasserfach98, 661 (1957).
S. Chanceller, Nature185, 841 (1960).
H. Raymond, A. Pierson, Anal. Chem.,28, 1213 (1956)
A. Rijeke, A. Johnson, E. Oster, J. Biol. Mafer. Res.11, 211 (1977).
C. Alley, J. Bocks, G. Choudhary, Anal. Chem.48, 387 (1976).
J. Tanguay, Method Modification for Methyl methacrylate, NIOSH, DPSE, MRSB, unpublished (NIOSH), 1988.
H. Hollefeeld, R. Snyder, C. Breeder, J. Chromatogr. Sci.19, 514 (1981).
B. Kolb, Headspace Gaschromatographie mit Kapillartrennsäulen, Würzburg, 1986, p. 27.
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Tashkov, W., Getchev, V. Determination of unpolymerized methyl methacrylate in contact lenses by headspace gas chromatography. Chromatographia 37, 546–548 (1993). https://doi.org/10.1007/BF02275795
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DOI: https://doi.org/10.1007/BF02275795