Pharmaceutisch Weekblad

, Volume 2, Issue 1, pp 562–567 | Cite as

Stability of corticosteroids under anaerobic conditions

III. 17-ketosteroid
  • D. Dekker
  • D. J. Buijs
Original Articles
  • 12 Downloads

Abstract

One of the identified decomposition products during the anaerobic decomposition of prednisolone is the 17-ketosteroid.

The Chromatographic properties, the isolation and the structure elucidation of the 17-ketosteroid are given. Mechanisms leading to this compounds are discussed.

Keywords

Public Health Internal Medicine Corticosteroid Prednisolone Anaerobic Condition 

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Copyright information

© Bohn, Scheltema & Holkema 1980

Authors and Affiliations

  • D. Dekker
    • 1
  • D. J. Buijs
    • 1
  1. 1.Department of Analytical Pharmacy, Faculty of PharmacyState University of UtrechtGH UtrechtThe Netherlands

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