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Human Genetics

, Volume 94, Issue 1, pp 74–76 | Cite as

Supernumerary chromosomes and spermatogenesis in a human male carrier

  • H. Jaafar
  • O. Gabriel-Robez
  • F. Vignon
  • E. Flori
  • Y. Rumpler
Short Communication

Abstract

A 57-year-old patient was referred because of primary sterility. Spermogram and testicular histology showed moderate oligospermia and irregular hypospermatogenesis. Karyotypic analysis revealed the presence of a metacentric supernumerary chromosome. Synaptonemal complex analysis using the surface-spreading technique was undertaken to study the meiotic behaviour of the extra chromosome during the pachytene stages. The relationship of the extra chromosome to the infertility of the carrier is discussed.

Keywords

Internal Medicine Metabolic Disease Infertility Complex Analysis Synaptonemal Complex 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • H. Jaafar
    • 1
  • O. Gabriel-Robez
    • 1
  • F. Vignon
    • 2
  • E. Flori
    • 3
  • Y. Rumpler
    • 1
  1. 1.Institut d'Embryologie, Université Louis PasteurFaculté de médecineStrasbourg CedexFrance
  2. 2.Clinique UrologiqueHôpital Civil de StrasbourgStrasbourgFrance
  3. 3.Service d'Histologie, d'Embryologie et de CytogénétiqueHôpital HautepierreStrasbourg CedexFrance

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