Summary
Equilibrium headspace gas chromatography has been applied to the determination of the partition coefficients of volatile compounds in water-air systems. Only techniques that are suited to a fully automatic headspace procedure using the pneumatic headspace sampling-technique have been considered. Particularly simple is the technique of “vapor phase calibration —VPC” where an external vapor standard is used to calibrate the concentration of the volatile analyte in the headspace, while the concentration in the sample is found from the difference in the total amount in the vial. This technique is described in detail for 2-butanone in water. Finally, the water-air partition coefficients of several selected volatile compounds at different temperatures are listed together with their temperature functions.
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Abbreviations
- AC :
-
Peak area of analyte from external vapor standard
- AS :
-
Peak area of analyte from headspace sample
- aC :
-
slope of regression of analyte from external vapor standard
- aS :
-
slope of regression of analyte from sample vial
- CS :
-
Concentration of analyte in sample
- CG :
-
Concentration of analyte in gas phase of sample vial
- CG C :
-
Vapor concentration of analyte in external vapor standard
- K:
-
Partition coefficient
- mo :
-
Total amount of analyte in vial
- mG :
-
Amount of analyte in gas phase
- mS :
-
Amount of analyte in sample
- Pa :
-
Atmospheric pressure
- Ph :
-
Headspace pressure in pressurized vial (Ph=Pa+PGC) with PGC as excess pressure given by pressure of GC
- VG :
-
Volume of gas phase (headspace) in vial
- VS :
-
Volume of sample in vial
- VV :
-
Volume of headspace vial
- β:
-
Phase ratio (β=VG/VS)
- @:
-
Calibration factor
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Dedicated to Professor Leslie S. Ettre on the occasion of his 70th birthday.
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Kolb, B., Welter, C. & Bichler, C. Determination of partition coefficients by automatic equilibrium headspace gas chromatography by vapor phase calibration. Chromatographia 34, 235–240 (1992). https://doi.org/10.1007/BF02268351
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DOI: https://doi.org/10.1007/BF02268351