Chromatographia

, Volume 26, Issue 1, pp 237–243 | Cite as

Expert systems for chemical analysis (ESPRIT Project 1570)

  • D. Goulder
  • T. Blaffert
  • A. Blokland
  • L. Buydens
  • A. Chhabra
  • A. Cleland
  • N. Dunand
  • H. Hindriks
  • G. Kateman
  • H. van Leeuwen
  • D. Massart
  • A. Mulholland
  • G. Musch
  • P. Naish
  • A. Peeters
  • G. Postma
  • P. Schoenmakers
  • M. de Smet
  • B. Vandeginste
  • J. Vink
Article

Summary

This paper gives an overview of the structure and processes going on in the project Expert Systems for Chemical Analysis (ESCA), an international project within the ESPRIT research programme of the European Community. The application area, HPLC method development, is explained and broken down into four domains. The methods used for representing knowledge in the project are discussed.

Key Words

High-performance liquid chromatography Expert systems System selection and optimisation Application to pharmaceutical analysis Selectivity optimisation Method validation 

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References

  1. [1]
    P. J. Schoenmakers, M. Mulholland, Chromatographia,25, 737 (1988).Google Scholar
  2. [2]
    H. Hindriks, A. Blokland, J. Vink, L. Buydens, A. Peeters, M. de Smet, D. L. Massart, 17th International Symposium on Chromatography, Vienna, September 25–30, 1988.Google Scholar
  3. [3]
    P. J. Schoenmakers, Optimisation of Chromatographic Selectivity: a guide to method development, Elsevier, Amsterdam 1986.Google Scholar
  4. [4]
    D. L. Massart, L. Buydens, A. Peeters, P. J. Schoenmakers, 17th International Symposium on Chromatography, Vienna, September 25–30, 1988.Google Scholar
  5. [5]
    P. J. Schoenmakers, G. Musch, A. Cleland, N. Dunand, P. J. P. K. de Bokx, 17th International Symposium on Chromatography, Vienna, September 25–30, 1988.Google Scholar
  6. [6]
    M. Mulholland, H. van Leeuwen, B. Vandeginste, 17th International Symposium on Chromatography, Vienna, September 25–30, 1988.Google Scholar
  7. [7]
    M. Mulholland, H. van Leeuwen, B. Vandeginste, 17th International Symposium on Chromatography, Vienna, September 25–30, 1988.Google Scholar
  8. [8]
    T. de Marco, Structured Analysis and System Design, Prentice-Hall, New York, 1979.Google Scholar
  9. [9]
    M. de Smet, G. Hoogewijs, M. Puttermans, D. L. Massart, Anal. Chem.,56, 2662 (1984).Google Scholar
  10. [10]
    G. Musch, M. de Smet, D. L. Massart, J. Chromatogr.348, 97 (1985).Google Scholar
  11. [11]
    G. Musch, D. L. Massart, J. Chromatogr.370, 1 (1986).Google Scholar
  12. [12]
    M. de Smet, G. Musch, A. Peeters, L. Buydens, D. L. Massart, accepted for publication in Analytical Chemistry.Google Scholar

Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1988

Authors and Affiliations

  • D. Goulder
    • 1
  • T. Blaffert
    • 2
  • A. Blokland
    • 3
  • L. Buydens
    • 4
  • A. Chhabra
    • 1
  • A. Cleland
    • 1
  • N. Dunand
    • 1
  • H. Hindriks
    • 3
  • G. Kateman
    • 5
  • H. van Leeuwen
    • 5
  • D. Massart
    • 4
  • A. Mulholland
    • 1
  • G. Musch
    • 4
  • P. Naish
    • 1
  • A. Peeters
    • 4
  • G. Postma
    • 5
  • P. Schoenmakers
    • 6
  • M. de Smet
    • 4
  • B. Vandeginste
    • 5
  • J. Vink
    • 3
  1. 1.Philips ScientificCambridgeUK
  2. 2.Philips ResearchHamburgFRG
  3. 3.Organon InternationalOssThe Netherlands
  4. 4.Free University of BrusselsBelgium
  5. 5.Catholic University of NijmegenThe Netherlands
  6. 6.Philips ResearchEindhovenThe Netherlands

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