Clinical Autonomic Research

, Volume 7, Issue 2, pp 93–96 | Cite as

Reproducibility of exercise-induced modulation of cardiovascular responses to cold stress

  • H. M. K. Rashed
  • G. Leventhal
  • E. C. Madu
  • R. Reddy
  • S. Cardoso
Research Paper


The modulation of cardiovascular responses to the cold pressor test (CPT) as produced by exercise was studied in 13 volunteers. The reproducibility of the measurements selected for the study, i.e. heart rate (HR), blood pressure (BP), blood flow (BF) and skin temperature (ST), was investigated through repeat experiments in the fall of 1994 and the winter of 1995. HR was monitored before, during and after a 10-min period of bicycling at 70% of reserve HR. BP, cutaneous BF and ST were measured before and after exercise. Two CPTs (hand into ice-cold water for 1 min) were performed: one preceding exercise and another at 3 min after exercise. The results obtained allow us to conclude that in non-hypertensive volunteers (1) the pronounced cardiovascular responses (ST, BF and BP) induced by CPT are reproducible (p>0.2) when compared to basal level values and (2) cardiovascular responses to cold stress are significantly attenuated by exercise (p<0.03). Our study, therefore, supports and validates the use of our coupled exercise-CPT method in ongoing epidemiological studies attempting to identify individuals at risk for the development of hypertension as well as those most likely to benefit from preventative exercise programs.


reproducibility autonomic functions exercise cold pressor test 


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Copyright information

© Rapid Science Publishers 1997

Authors and Affiliations

  • H. M. K. Rashed
    • 1
  • G. Leventhal
    • 3
  • E. C. Madu
    • 2
  • R. Reddy
    • 2
  • S. Cardoso
    • 1
  1. 1.Autonomic Function Laboratory, Department of PharmacologyUniversity Of TennesseeMemphisUSA
  2. 2.Autonomic Function Laboratory, Department of MedicineUniversity Of TennesseeMemphisUSA
  3. 3.Collierville High SchoolColliervilleUSA

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