, Volume 13, Issue 5, pp 259–262 | Cite as

Two-dimensional separations and behaviour of alkaloids of various polarities on unmodified silica gel in polar and very polar neutral or acidic mobile phases

  • R. L. Munier
  • S. Meunier


New separation procedures for alkaloids of similar polarity and structure or of very different polarity and structure, based upon two-dimensional thin-layer chromatography on unmodified silica gel under mild conditions are described. Separation factors and separation mechanisms based on the structure of the bases and mobile phase composition are discussed for some examples of very efficient procedures.

Key Words

Two-dimensional separations Alkaloids Chromatography under mild conditions Unmodified silica gel TLC 


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Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1980

Authors and Affiliations

  • R. L. Munier
    • 1
  • S. Meunier
    • 1
  1. 1.C.N.R.S.Institut PasteurFrance

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