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Genetic structures in the Po Delta: Principal components, systemic functions and the relative age of the beta-thalassemia polymorphism

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Summary

The principal component representations of the genetic structure of the human population of the Po Delta, obtained from 7 polymorphic loci, are compared with the representations obtained from the systemic function of gene frequencies devised by Womble 1951. It is noted that, when tridimensional representations are used, some consistency is visible in the results of the two methods for the description of the genetic population structure in the area under study. Both methods indicate that the present structure of the balanced polymorphism for beta-thalassemia in the area appears to be more recent than the structure of the neutral polymorphisms studied.

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References

  • Barbujani G, Oden NL, Sokal RR (1989) Detection of non-stationary variation in gene frequency maps (abstract). 2nd Congress of the European Society of Evolutionary Biology, Rome 1989, p11

  • Barrai I, Rosito A, Cappellozza G, Cristofori G, Vullo C, Scapoli C, Barbujani G (1984) Beta-thalassemia in the Po Delta: selection, geography and population structure. Am J Hum Genet 36:1121–1134

    Google Scholar 

  • Barrai I, Beretta M, Mamolini E, Scapoli C, Barale R, Ravani A (1989a) Principal components and the systemic function in the Po Delta (abstract). Atti Assoc Genet Ital 35:31–34

    Google Scholar 

  • Barrai I, Beretta M, Mamolini E, Gavina R, Barale R, Scapoli C, Canella R, Vullo C, Ravani A (1989b) Kinship and migration in the Po Delta (abstract). Atti Assoc Genet Ital 35:27–29

    Google Scholar 

  • Barrai I, Canella R, Beretta M, Mamolini E, Barale R, Scapoli C, Ravani A (1991) Kinship structures and migration in the Po Delta. Ann Hum Genet 55:251–259

    Google Scholar 

  • Beretta M, Mazzetti P, Mamolini E, Gavina R, Barale R, Vullo C, Ravani A, Franze' A, Sapigni T, Soracco E, Davi D, Ricci N, Cappello N, Rendine S, Piazza A, Barrai I (1989) Genetic structure of the human population of the Po Delta. Am J Hum Genet 45:49–62

    Google Scholar 

  • Menozzi P, Piazza A, Cavalli-Sforza LL (1978) Synthetic maps of human gene frequencies in Europeans. Science 201:786–792

    Google Scholar 

  • Piazza A, Menozzi P, Cavalli-Sforza LL (1981) Synthetic gene frequency maps of man and selective effects of climate. Proc Natl Acad Sci USA 78:2638–2642

    Google Scholar 

  • Rendine S, Piazza A, Cavalli-Sforza LL (1986) Simulation and separation by principal components of multiple demic expansions in Europe. Am Nat 128:681–706

    Google Scholar 

  • Sowerbutts WTC (1988) WhizPlot. Users Manual, Basic Version. WTC Scientific, Macclesfield, UK

    Google Scholar 

  • Womble WH (1951) Differential systematics. Science 114:315–322

    Google Scholar 

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This paper is in celebration of the Sixth Centennial Jubilee of the University of Ferrara, 1391-1991

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Barrai, I., Beretta, M., Mamolini, E. et al. Genetic structures in the Po Delta: Principal components, systemic functions and the relative age of the beta-thalassemia polymorphism. Hum Genet 88, 613–618 (1992). https://doi.org/10.1007/BF02265284

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  • DOI: https://doi.org/10.1007/BF02265284

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