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Renal transport of aromatic acids in patients with phenylketonuria

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Journal of Inherited Metabolic Disease

Abstract

Renal clearance of phenylpyruvic acid is maximal at a plasma concentration of 40–60 µmol/l. This concentration is obtained with plasma phenylalanine concentrations of 1.0–1.2mmol/l, the threshold for separating classical phenylketonuria from phenylketonuria variants.

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Authors and Affiliations

  1. Institute of Human Genetics, Nikolausberger Weg 5a, D-3400, Göttingen, FRG

    U. Langenbeck

  2. Children's Hospital, D-3400, Göttingen, FRG

    A. Behbehani

  3. Department of Clinical Chemistry, University of Göttingen, D-3400, Göttingen, FRG

    H. Luthe

Authors
  1. U. Langenbeck
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  2. A. Behbehani
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  3. H. Luthe
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Langenbeck, U., Behbehani, A. & Luthe, H. Renal transport of aromatic acids in patients with phenylketonuria. J Inherit Metab Dis 4, 69–70 (1981). https://doi.org/10.1007/BF02263595

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  • DOI: https://doi.org/10.1007/BF02263595

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