Abstract
The ratio of urocanic acid to histidine in stratum corneum can be used to differentiate patients with histidinaemia from normal subjects. The histidinaemia heterozygotes have intermediate ratios.
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Baden, H. P. and Pathak, M. A. The metabolism and function of urocanic acid in skin.J. Invest. Dermatol. 48 (1967) 11–17
Ghadimi, H., Partington, M. W. and Hunter, A. A familial disturbance of histidine metabolism.N. Engl. J. Med. 265 (1961) 221–224
Kihara, H., Boggs, D. E., Lassila, E. L. and Wright, S. W. Histidinemia.Biochem. Med. 2 (1968) 243–249
La Du, B. N., Howell, R. R., Jacoby, G. A., Seegmiller, J. E. and Zannoni, V. G. The enzyme defect in histidinemia.Biochem. Biophys. Res. Commun. 7 (1962) 398–402
Levy, H. L., Baden, H. P. and Shih, V. E. A simple indirect method of detecting the enzyme defect in histidinemia.J. Pediatr. 75 (1969) 1056–1058
Zannoni, V. G. and La Du, B. N. Detection of histidine α-deaminase in human stratum corneum and its absence in histidinaemia.Biochem. J. 88 (1963) 160–162
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Ito, F., Ota, H., Aoki, K. et al. Urocanic acid contents in histidinaemic infant and developing rat epidermis. J Inherit Metab Dis 4, 55–56 (1981). https://doi.org/10.1007/BF02263588
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DOI: https://doi.org/10.1007/BF02263588