Summary
The performance of injection valves with both curtain- and single-flow column couplings has been evaluated using reverse-phase octadecylsilane columns and a standard test mixture. The results are compared with those obtained from septum and stopped-flow syringe injections.
Stopped-flow valve injection has been examined similarly. Configurations and couplings which give optimum efficiency and reproducibility are recommended.
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References
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Kelsey, R.J., Loscombe, C.R. A comparative study of injection techniques in high-performance liquid chromatography. Chromatographia 12, 713–715 (1979). https://doi.org/10.1007/BF02262448
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DOI: https://doi.org/10.1007/BF02262448