Summary
Utilization of micro-HPLC is described for the direct measurement of the partition coefficients needed in studying the quantitative structure — activity relationships (QSAR). The method involves analyzing the solutes in acetonitrile — water as the mobile phase on commercially available reversed-phase stationary phases.
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Jinno, K. Utilization of micro-HPLC for the direct measurement of the partition coefficients needed in studying the quantitative structure — activity relationships. Chromatographia 15, 723–725 (1982). https://doi.org/10.1007/BF02261893
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DOI: https://doi.org/10.1007/BF02261893