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European Journal of Nuclear Medicine

, Volume 20, Issue 1, pp 80–82 | Cite as

Indium-111-labelled antimyosin antibody imaging in a patient with cardiac sarcoidosis

  • Wolfram H. Knapp
  • Anna Bentrup
  • Harm Ohlmeier
Case Report

Abstract

The aetiology of cardiac dysfunction caused by sarcoid granulomatous inflammation may be difficult to clarify, and the potential of imaging methods is limited. We report on a patient who presented with acute biventricular decompensation. Pulmonary sarcoidosis was confirmed after hospitalization. Four weeks after the initiation of corticosteroid treatment, scintigraphy with indium-111-labelled antimyosin antibody Fab fragments (AMAB) revealed distinct activity accumulation in major parts of the left ventricular wall (heart-lung ratio: 1.6) 72 h following injection. There may be a role for AMAB scintigraphy in the early detection of cardiac sarcoidosis.

Key words

Sarcoidosis Sarcoid heart disease Indium-111-labelled antimyosin antibodies Myocardial scintigraphy 

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Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • Wolfram H. Knapp
    • 1
  • Anna Bentrup
    • 1
  • Harm Ohlmeier
    • 2
  1. 1.Institute of Nuclear MedicineUniversity Hospital of the Ruhr-Universität BochumBad OeynhausenGermany
  2. 2.Department of Cardiology, Heart Center North-Rhine WestphaliaUniversity Hospital of the Ruhr-Universität BochumBad OeynhausenGermany

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