European Journal of Nuclear Medicine

, Volume 20, Issue 1, pp 80–82 | Cite as

Indium-111-labelled antimyosin antibody imaging in a patient with cardiac sarcoidosis

  • Wolfram H. Knapp
  • Anna Bentrup
  • Harm Ohlmeier
Case Report


The aetiology of cardiac dysfunction caused by sarcoid granulomatous inflammation may be difficult to clarify, and the potential of imaging methods is limited. We report on a patient who presented with acute biventricular decompensation. Pulmonary sarcoidosis was confirmed after hospitalization. Four weeks after the initiation of corticosteroid treatment, scintigraphy with indium-111-labelled antimyosin antibody Fab fragments (AMAB) revealed distinct activity accumulation in major parts of the left ventricular wall (heart-lung ratio: 1.6) 72 h following injection. There may be a role for AMAB scintigraphy in the early detection of cardiac sarcoidosis.

Key words

Sarcoidosis Sarcoid heart disease Indium-111-labelled antimyosin antibodies Myocardial scintigraphy 


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Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • Wolfram H. Knapp
    • 1
  • Anna Bentrup
    • 1
  • Harm Ohlmeier
    • 2
  1. 1.Institute of Nuclear MedicineUniversity Hospital of the Ruhr-Universität BochumBad OeynhausenGermany
  2. 2.Department of Cardiology, Heart Center North-Rhine WestphaliaUniversity Hospital of the Ruhr-Universität BochumBad OeynhausenGermany

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