Summary
Mutual diffusion coefficients of two gases A and B can be determined in an empty gas chromatographic column by letting component B enter at an intermediate position of the column and continuously flow through a part only of it, as a carrier gas. The other component A is injected in a small amount instantaneously at the closed end of the column with the detector placed at the other end. By repeatedly stopping and then restoring after a short time the flow of B, narrow extra peaks are produced on the chromatographic elution curve, owing to diffusion of A into B. An equation is derived giving the area under the curve of each stop-peak as a function of time of the corresponding stop. Plotting the experimental data according to this equation permits the determination of the diffusion coefficient of A into B. Some results obtained by this method show negligible variations with changes in the experimental parameters.
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References
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Katsanos, N.A., Karaiskakis, G., Vattis, D. et al. Diffusion coefficients from stopped-flow gas chromatography. Chromatographia 14, 695–698 (1981). https://doi.org/10.1007/BF02259457
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DOI: https://doi.org/10.1007/BF02259457