Abstract
Quaternary ammonium salts containing propargyl and 3-(2-methyltetrazol-5-yl)propargyl groups undergo base-catalyzed cyclization at room temperature with self heating to form condensed heterocyclic systems containing the tetrazole ring. Heating at 90–92°C for 2 h is necessary to cyclize the allyl analogs of the starting salts.
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References
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Additional information
Communication 234 of the series “Research on Amines and Ammonium Compounds.” For 233, see [1].
Institute of Organic Chemistry, National Academy of Sciences of the Republic of Armenia, Erevan 375094. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 390–394, March, 1999.
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Chukhadzhyan, E.O., Shakhatuni, K.G., Chukhadzhyan, E.O. et al. Synthesis of condensed systems containing the tetrazole ring by base-catalyzed intramolecular cyclization of quaternary ammonium salts. Chem Heterocycl Compd 35, 343–347 (1999). https://doi.org/10.1007/BF02259366
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DOI: https://doi.org/10.1007/BF02259366