, Volume 14, Issue 5, pp 257–268 | Cite as

Very-high-speed liquid column chromatography the system and selected applications

  • J. L. DiCesare
  • M. W. Dong
  • L. S. Ettre


Instrumentation needed to achieve very high performance (plate/s) liquid chromatography is discussed. With recently available systems using relatively short (100–125 mm) columns of conventional internal diameter (4–6 mm) and packed with 3–5 μm particles, analysis in very short times (usually 1–3 min) is possible. Coupling such columns in series provide very high performance in a time still significantly less than previously encountered. Performance of such liquid chromatographic systems is illustrated with a number of practical examples including analgesic tablets, cosmetics, soft drinks, antioxidants and polyaromatic hydrocarbons.

Key Words

Liquid chromatography High-speed analysis LC instrumentation Polyaromatic hydrocarbons 


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Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1981

Authors and Affiliations

  • J. L. DiCesare
    • 1
  • M. W. Dong
    • 1
  • L. S. Ettre
    • 1
  1. 1.Chromatography DivisionThe Perkin-Elmer CorporationNorwalkUSA

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