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Factors effecting film thickness in glass capillary chromatographic columns coated by the “Mercury Plug” method

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Summary

The “Mercury Plug” Dynamic (MPD) method, recently introduced for the coating of glass capillary columns, has several advantages over other methods. However, while general rules governing the film thickness in both the “static” and the conventional dynamic coating methods have been intensively studied, this in not the case for the MPD method. In this paper, the effect of several parameters determining the film thickness were studied. The volumetric method applied to measure the film thickness was found to be faster and more accurate than the chromatographic methods used by other authors. The effect of viscosity of the coating solution and the velocity of the plug were studied in detail and as a result it was found that the same type of equation as the one describing the film thickness in the dynamic method, was applicable also to the MPD technique. A model is suggested to explain this result.

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Author notes

  1. G. Alexander

    Present address: Research Laboratory for Inorganic Chemistry, Hungarian Academy of Sciences, P. O. Box 132, H-1502, Budapest 112, Hungary

Authors and Affiliations

  1. Yale University Medical School, 06510, New Haven, Conn., USA

    G. Alexander & S. R. Lipsky

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  1. G. Alexander
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  2. S. R. Lipsky
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Alexander, G., Lipsky, S.R. Factors effecting film thickness in glass capillary chromatographic columns coated by the “Mercury Plug” method. Chromatographia 10, 487–491 (1977). https://doi.org/10.1007/BF02257364

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