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Reactions of aminoquinolines with unsaturated carboxylic acids. 3. Synthesis of n-quinolylaspartic acids and their derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Reaction of aminoquinolines with maleic acid and its diethyl ester gave N-quinolylaspartic acids or their esters. In aqueous media 4-aminoquinoline formed a maleate or betaine. Hydrazides of aspartic acids were prepared, and N-(3- and 6-quinolyl)aspartic acids were converted into 5-carboxymethyl-l-quinolylimidazolindin-4-one-2-thiones.

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Additional information

For Communication 2, see [1].

Kaunus Technological University, Kaunas 3028, Lithuania Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 925–931, July, 2000.

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Beresnevicius, Z.I., Viliunas, V. Reactions of aminoquinolines with unsaturated carboxylic acids. 3. Synthesis of n-quinolylaspartic acids and their derivatives. Chem Heterocycl Compd 36, 811–817 (2000). https://doi.org/10.1007/BF02256915

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  • DOI: https://doi.org/10.1007/BF02256915

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