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Gastrointestinal Radiology

, Volume 1, Issue 1, pp 241–243 | Cite as

Lymphangiectasia of the small intestine: description and pathophysiology of the roentgenographic signs

  • William W. Olmsted
  • John E. Madewell
Article

Abstract

Waldmann in 1961 redefined primary protein-losing gastroenteropathy and renamed the condition “lymphangiectasia”. This abnormality, usually seen in infancy, is characterized by enlargement of folds and signs of hypersecretion in the small bowel. Enlargement of folds occurs secondary to edema of the valvulae conniventes and lymphatic dilatation. Hypersecretion may be the result of rupture of dilated lymphatics or transudation of protein across an intact capillary epithelium. The clinical, roentgenographic, and pathologic findings are described. The pathophysiology of this condition is discussed.

Key words

Lymphangiectasia Protein-losing enteropathy Small bowel Lymphatics 

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References

  1. 1.
    Waldmann T, Steinfeld J, Dutcher T, et al.: The role of the gastrointestinal system in “idiopathic hypoproteinemia”.Gastroenterology 41: 197–207, 1961Google Scholar
  2. 2.
    Pomerantz M, Waldmann T: Systemic lymphatic abnormalities associated with gastrointestinal protein loss secondary to intestinal lymphangiectasia.Gastroenterology 45: 703–711, 1963Google Scholar
  3. 3.
    Bookstein J, French A, Pollard H: Protein-losing gastroenteropathy: Concepts derived from lymphangiography.Am J Dig Dis 10: 573–581, 1965Google Scholar
  4. 4.
    Marshak R, Hazzi C, Lindner A, et al.: Small bowel in immunoglobulin deficiency syndromes.Am J Roentgenol Radium Ther Nucl Med 122: 227–240, 1974Google Scholar
  5. 5.
    Takashima T, Takekoshi N: Lymphographic evaluation of abnormal lymph flow in protein-losing gastroenteropathy secondary to chronic constrictive pericarditis.Radiology 90: 502–506, 1968Google Scholar
  6. 6.
    Wilkinson P, Pinto B, Senior J: Reversible protein-losing enteropathy with intestinal lymphangiectasia secondary to chronic constrictive pericarditis.N Engl J Med 273: 1178–1181, 1965Google Scholar
  7. 7.
    Waldmann T: Progress in gastroenterology: Protein-losing enteropathy.Gastroenterology 50: 422–443, 1966Google Scholar
  8. 8.
    Herskovic T, Winawer S, Goldsmith R, et al.: Hypoproteinemia in intestinal lymphangiectasia: Contribution of albumin “trapping” in the lymphedematous extremity.Pediatrics 40: 345–353, 1967Google Scholar
  9. 9.
    Olmsted W, Reagin D: The pathophysiology of small bowel fold enlargement. Unpublished dataGoogle Scholar
  10. 10.
    Shimkin P, Waldmann T, Krugman R: Intestinal lymphangiectasia.Am J Roentgenol Radium Ther Nucl Med 110: 827–841, 1970Google Scholar
  11. 11.
    Mistilis S, Skyring A, Stephen D: Intestinal lymphangiectasia: Mechanism of enteric loss of plasma-protein and fat.Lancet 1: 77–79, 1965Google Scholar
  12. 12.
    Gold R, Youker J: Idiopathic intestinal lymphangiectasis (primary protein-losing enteropathy): Lymphographic verification of enteric and peritoneal leakage of chyle.Radiology 109: 315–316, 1973Google Scholar

Copyright information

© Springer-Verlag 1976

Authors and Affiliations

  • William W. Olmsted
    • 1
  • John E. Madewell
    • 1
  1. 1.Department of Radiologic PathologyArmed Forces Institute of PathologyWashington D.C.USA

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