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Chemistry of Heterocyclic Compounds

, Volume 35, Issue 11, pp 1349–1356 | Cite as

Synthesis of 1,4-dihydroimidazo[5,1-c]-1,2,4-triazin-4-ones and imidazo[5,1-c]-1,2,4-triazoles

  • M. A. Bezmaternykh
  • V. S. Mokrushin
  • T. A. Pospelova
Article

Abstract

Azo compounds obtained by the coupling of 5-diazoimidazoles with diethyl esters of nitro-, chloro-, bromo-, and acetylaminomalonic acids under conditions of base catalysis are cyclized to give 1,4-dihydroimidazo[5,1-c]-1,2,4-triazin-4-ones or imidazo[5,1-c]-1,2,4-triazoles. The chloro, bromo, and nitro groups in the bicyclic products are readily replaced by action of nucleophiles. The imidazotriazinones are converted to chloroimidazotriazines by reaction with thionyl chloride or phosphorus oxychloride

Keywords

Chloride Ester Phosphorus Organic Chemistry Catalysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic/Plenum Publishers 1999

Authors and Affiliations

  • M. A. Bezmaternykh
  • V. S. Mokrushin
  • T. A. Pospelova

There are no affiliations available

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