Chemistry of Heterocyclic Compounds

, Volume 35, Issue 12, pp 1441–1442 | Cite as

Synthesis of 3-cyano-3-ethoxycarbonyl-4-methyl-6-phenylpyridine-2(1H)-thione and its alkylation

  • S. G. Krivokolysko
  • V. D. Dyachenko
  • V. P. Litvinov
Article

Abstract

The condensation of acetaldehyde with cyanothioacetamide and ethyl benzoylacetate in the presence of N-methylmorpholine leads to the formation of 3-cyano-5-ethoxycarbonyl-4-methyl-6-phenylpyridine-2(1H)-thione. Alkylation of the last afforded the corresponding substituted 2-alkythiopyridines.

Keywords

Acetaldehyde Ethyl Organic Chemistry Alkylation Thione 

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Copyright information

© Kluwer Academic/Plenum Publishers 1999

Authors and Affiliations

  • S. G. Krivokolysko
  • V. D. Dyachenko
  • V. P. Litvinov

There are no affiliations available

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