Tropical Animal Health and Production

, Volume 5, Issue 3, pp 166–173 | Cite as

Attempts at immunizing cattle against anaplasmosis using a killed vaccine

  • N. McHardy
  • Ruth M. Simpson
Article

Summary

Antigens were prepared from the washed erythrocytes of cattle carrying high parasitaemias of a South African and a Kenyan strain ofAnaplasma marginale. Saponin was used as adjuvant. Following syringe challenge with virulentA. marginale, the vaccine produced a delay in infection compared with unvaccinated controls, and in some cases reduced the severity of the infection.

Keywords

Public Health Syringe Veterinary Medicine Saponin Como 

Essais d'immunisation de bovins contre l'anaplasmose au moyen d'un vaccin tué

Résumé

Des antigènes ont été préparés à partir d' érythrocytes lavés de bovins présentant une parasitémie élevée avec une souche Sud-Africaine et une souche Kenyane d'Anaplasma marginale. La saponine a été utilisée adjuvant. A la suite d'inoculations d'épreuves avec une souche virulente d'A. marginale, les animaux vaccinés ont fait, comparativement aux témoins non vaccinés, une infection tardive, et, dans quelques cas, l'infection a été moins sévère.

Intentos de inmunizacion de bovinos contra anaplasmosis con vacuna inactivada

Sumario

Se prepararon antígenos de eritrocitos de bovinos previo lavado. Estos eritrocitos eran portadores de una alta parasitemia deAnaplasma marginale correspondiente a las cepas Sud Africana y a una cepa de Kenya. Saponina fue usada como adyuvante. Después del desafio mediante inyeccion deA. marginalle viruento la vacuna produjo un retraso en la infección comparado a controles no vacunados, y en algunos casos redujo la severidad de la infección.

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Copyright information

© E. & S. Livingstone 1974

Authors and Affiliations

  • N. McHardy
    • 1
  • Ruth M. Simpson
    • 1
  1. 1.Wellcome Research LaboratoryP.O. KabeteKenya

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