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Studies on helminthosis at the centre for tropical veterinary medicine (CTVM)

Etudes Sur Les Helminthiases A CTVM

Estudios Sobre Enfermedades Causadas Por Helmintos En El CTVM

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Summary

The research work relating to helminths, which has been conducted within the Helminthology Section of the CTVM, often in collaboration with colleagues from the tropics is reviewed and placed into a historical perspective. The research has, in the main, concentrated on the trematodesFasciola hepatica andFasciola gigantica and the cestodesTaenia saginata andTaenia solium, but work on other parasites including gastro-intestinal nematodes is also considered. All of these parasites are of obvious veterinary/economic importance particularly in the tropics and subtropics. While the zoonotic importance ofT. saginata andT. solium has been recognised for many years, it is only more recently that the zoonotic impact ofFasciola spp. has been generally acknowledged.

Résumé

Le travail de recherche portant sur les helminthes, qui a été mené dans le groupe Helminthologie à CTVM, souvent en collaboration avec des collègues des pays tropicaux, est passé en revue et mis dans une perspective historique. La recherche a principalement porté sur les trematodesFasciola hepatica etFasciola gigantica et sur les cestodesTaenia saginata etTaenia solium, cependant d'autres travaux ont également porté sur d'autres parasites et sur des nématodes gastro-intestinaux.

Tous ces parasites sont d'une importance économique/vétérinaire évidente et ceci particulièrement dans les pays tropicaux et sub-tropicaux. Tandis que l'importance deT. saginata etT. solium, sur la zoonose, a toujours été reconnue, ce n'est que récemment que l'impact deFasciola spp sur la zoonose a été repertorié.

Resumen

El artículo revisa y sitúa en una perspectiva histórica la investigación sobre helmintos realizada en la sección de helmintología del CTVM, a menudo en colaboración con otros investigadores de países tropicales. La investigación se ha centrado principalmente en los trematodosFasciola hepatica y Fasciola gigantica y en los cestodosTaenia saginata y Taenia solium, aunque en el artículo se incluye también el trabajo realizado con nematodos gastrointestinales y otros parásitos. Todos los parásitos mencionados tienen una importancia obvia desde el punto de vista veterinario y económico, particularmente en los trópicos y subtrópicos. Mientras que la importancia deT. saginata yT. solium como zoonosis ha sido siempre reconocida, el posible carácter zoonótico deFasciola spp. ha sido descubierto muy recientemente.

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References

  • Ajanusi, J. O. (1993). Immunochemistry ofFasciola hepatica in the rat model. Ph.D. Thesis, University of Edinburgh.

  • Ajanusi, J. O., Harrison, L. J. S. &Sewell, M.M.H. (1993).Fasciola hepatica: Biosynthetic radio-labelling and Western Blot analysis of excretory/secretory product.Transactions of the Royal Society of Tropical Medicine and Hygiene,87, 118.

    Google Scholar 

  • Ajanusi, J. O., Harrison, L. J. S. &Sewell, M. M. H. (1994). Excretory and secretory protein antigens ofFasciola hepatica in the rat.Transactions of the Royal Society of Tropical Medicine and Hygiene,88, 19.

    Google Scholar 

  • Al-Sammarrae, S. A. &Sewell, M. M. H. (1977a). Studies on the epidemiology ofDictyocaulus filaria infection in Blackface sheep on a low ground Scottish farm.Research in Veterinary Science,23, 336–339.

    Google Scholar 

  • Al-Sammarrae, S. A. &Sewell, M. M. H. (1977b). The relative susceptibility of Soay and Blackface sheep in natural infection withDictyocaulus filaria.Research in Veterinary Science,23, 383–384.

    Google Scholar 

  • Al-Sammarrae, S. A. &Sewell, M. M. H. (1978). The response of Suffolk lambs to an escalating experimental infection withDictyocaulus filaria.Research in Veterinary Science,25, 215–217.

    Google Scholar 

  • Bagadi, H. O. (1970). The pathogenesis of infectious necrotic hepatitis (black disease) of sheep. Ph.D. Thesis, University of Edinburgh.

  • Bagadi, H. O. &Sewell, M. M. H. (1973a). An epidemiological survey of infectious necrotic hepatitis (black disease) of sheep in southern Scotland.Research in Veterinary Science,15, 49–53.

    Google Scholar 

  • Bagadi, H. O. &Sewell, M. M. H. (1973b). Experimental studies on infectious necrotic hepatitis (black disease) of sheep.Research in Veterinary Science,15, 53–61.

    Google Scholar 

  • Bagadi, H. O. &Sewell, M. M. H. (1974a). A study of the route of dissemination of orally administered spores ofClostridium novyi Type B in guinea-pigs and sheep.Research in Veterinary Science,17, 179–181.

    Google Scholar 

  • Bagadi, H. O. &Sewell, M. M. H. (1974b). The influence ofpost-mortem autolysis on the diagnosis of infectious necrotic hepatitis (black disease).Research in Veterinary Science,17, 320–322.

    Google Scholar 

  • Bolbol, A. S., Hammond J. A. &Sewell, M. M. H. (1978). The response of rabbits to repeated infections withFasciola hepatica.Veterinary Science Communications,2, 231–235.

    Google Scholar 

  • Chiejina, S. N. &Sewell, M. M. H. (1974a). Experimental infections withTrichostrongylus colubriformis (Giles, 1892) Loos, 1905 in lambs: worm burden, growth rate and host resistance resulting from prolonged escalating infections.Parasitology,69, 301–314.

    Google Scholar 

  • Chiejina, S. N. &Sewell, M. M. H. (1974b). Worm burdens, acquired resistance and live weight gains in lambs during prolonged daily infections withTrichostrongylus colubriformis (Giles, 1892) Loos, 1905.Parasitology,69, 315–327.

    Google Scholar 

  • Clarkson, M. J., Escurra, E., Delgado E., Ortiz, P. O. &Claxton, J. R. (1995). The epidemioogy, immunology and control of fasciolosis in dairy cattle in Cajamarca, Peru, an area of high infection pressure. ODA/NRRD Animal Health Programme Project (1993–1996).

  • Claxton, J. R., Harrison, L. J. S. &Ortiz, P. O. (1995). Identificacion de la especie de Distoma en Cajamarca mediante la utilizacion de sondas de AND.Revista de Investigaciones Pecuarius Instituto Veterinario de Investigaciones Typicales y de Altura - IVITA (Peru),7, 133–136.

    Google Scholar 

  • Correa, D., Sandoval, M. A., Harrison, L. J. S., Parkhouse, R. M. E., Plancarte, A., Meza-Lucas, A. &Flisser, A. (1989). Human neurocyticercosis: comparison of monoclonal and polyclonal based EIA capture assays for the detection of parasite products in cerebrospinal fluid.Transactions of the Royal Society of Tropical Medicine and Hygiene,83, 814–816.

    Google Scholar 

  • Fakae, B. B. (1993). ConjointHeligmosomoides polygyrus andTrypanosoma congolense infection in mice. Ph.D. Thesis, University of Edinburgh.

  • Fakae, B. B., Harrison, L. J. S. &Sewell, M. M. H. (1993). Effect of conjoint infection withTrypanosoma congolense on protection against challenge infection withHeligmosomoides polygyrus.Transactions of the Royal Society of Tropical Medicine and Hygiene,87, 120.

    Google Scholar 

  • Fakae, B. B., Harrison, L. J. S., Ross, C. A. &Sewell, M. M. H. (1994).Heligmosomoides polygyrus andTrypanosoma congolense infections in mice: a laboratory model for concurrent gastro-intestinal nematode and trypanosome infections.Parasitology,108, 61–68.

    Google Scholar 

  • Fernandez, T. J. (1984). Studies on the passive transfer of resistance toFasciola hepatica. Ph.D. Thesis, University of Edinburgh.

  • Flach, E. J. &Sewell, M. M. H. (1987). Gastrointestinal nematodiasis in blackbuck (Antilope cervicapra) at Edinburgh Zoo.Journal of Zoo Animal Medicine,18, 56–61.

    Google Scholar 

  • Gallie, G. J. &Sewell, M. M. H. (1970). A technique for hatchingT. saginata eggs.The Veterinary Record,86, 749

    Google Scholar 

  • Gallie, G. J. &Sewell, M. M. H. (1972). The survival ofCysticercus bovis in resistant calves.The Veterinary Record,91, 481–482.

    Google Scholar 

  • Gallie, G. J. &Sewell, M. M. H. (1974a). The serological response of three month old calves to infection withTaenia saginata (Cysticercus bovis) and their resistance to reinfection.Tropical Animal Health and Production,6, 163–171.

    Google Scholar 

  • Gallie, G. J. &Sewell, M. M. H. (1974b). The serological response of calves infected neonatally withTaenia saginata (Cysticercus bovis).Tropical Animal Health and Production,6, 173–177.

    Google Scholar 

  • Gallie, G. J. &Sewell, M. M. H. (1976). Experimental immunisation of six month old calves against infection with the cysticercus stage ofTaenia saginata.Tropical Animal Health and Production,8, 233–242.

    Google Scholar 

  • Gallie, G. J. &Sewell, M. M. H. (1977). The effect of mebandazole on the cysticerci ofTaenia saginata in calves.Tropical Animal Health and Production,9, 24.

    Google Scholar 

  • Gallie, G. J. &Sewell, M. M. H. (1978). The efficacy of praziquantel against the cysticerci ofTaenia saginata in calves.Tropical Animal Health and Production,10, 36–38.

    Google Scholar 

  • Gallie, G. J. &Sewell, M. M. H. (1981a). Attempted immunisation of calves infected with the cysticercus stage ofTaenia saginata.Tropical Animal Health and Production,13, 213–216.

    Google Scholar 

  • Gallie, G. J. &Sewell, M. M. H. (1981b). Inoculation of calves and adult cattle with oncospheres ofTaenia saginata and their resistance to challenge infection.Tropical Animal Health and Production,13, 147–154.

    Google Scholar 

  • Gallie, G. J. &Sewell, M. M. H. (1983). Duration of immunity and absorption of cysticerci in calves after treatment ofTaenia saginata cysticercosis with praziquantel.Research in Veterinary Science,34, 127–130.

    Google Scholar 

  • Garden, N. J. (1978). Epidemiology of ascariasis in felidae at Edinburgh Zoological Park. M.Sc. Dissertation, University of Edinburgh.

  • Gemmell, M. A. (1986). A critical approach to the concepts of control and eradication of echinococcosis/hydatidosis and taeniasis/cysticercosis. In: Parasitology-Quo Vadit. Proceedings of the Sixth International Congress of Parasitology. Brisbane, Australia, pp 465–472.

  • Gibbens, J. C., Harrison, L. J. S. &Parkhouse, R. M. E. (1986). Immuno-globulin class responses toTaenia taeniaeformis in susceptible and resistant mice.Parasite Immunology,8, 491–502.

    Google Scholar 

  • Gray, D. (1974). A comparison of the pathogenesis of challenge and single infections withFasciola hepatica in sheep. M.Sc. Dissertation, University of Edinburgh.

  • Hammond, J. A. (1965). Observations on fascioliasis in Tanganyika.Bulletin of Epipoizootic Diseases of Africa,13, 55–65.

    Google Scholar 

  • Hammond, J. A. (1970). Studies on fascioliasis with special reference toFasciola gigantica in East Africa. Ph.D. Thesis, University of Edinburgh.

  • Hammond, J. A. (1972). Infections withFasciola spp. in wildlife in Africa.Tropical Animal Health and Production,4, 1–13.

    Google Scholar 

  • Hammond, J. A. (1973). Experimental chronicFasciola gigantica infection in sheep.Tropical Animal Health and Production,5, 12–21.

    Google Scholar 

  • Hammond, J. A. (1974). Human infection with the liver flukeFasciola gigantica.Transactions of the Royal Society of Tropical Medicine and Hygiene,68, 253–254.

    Google Scholar 

  • Hammond, J. A. &Sewell, M. M. H. (1974a). The pathogenic effect of experimental infections withFasciola gigantica in cattle.British Veterinary Journal,130, 453–446

    Google Scholar 

  • Hammond, J. A. &Sewell, M. M. H. (1974b). A comparison of infections of cattle withFasciola gigantica andF. hepatica.Proceedings of the Third International Congress of Parasitology,1, 500–501.

    Google Scholar 

  • Hammond, J. A. &Sewell, M. M. H. (1975) Experimental infections of cattle withFasciola gigantica: numbers of parasites recovered after varying periods of infection.Tropical Animal Health and Production,7, 105–113.

    Google Scholar 

  • Hammond, J. A., Fielding, D. &Nuru, H. (1994). Eucalyptus: a sustainable self-delivery molluscicide?Veterinary Research Communications,18, 359–365.

    Google Scholar 

  • Haroun, B. O. (1981). An investigation into the use of mice to monitor the protective effect ofFasciola immune serum. M.Sc. Dissertation, University of Edinburgh.

  • Haroun, E. M. &Hillyer, G. V. (1986). Resistance to fasciolosis-a review.Veterinary Parasitology,20, 63–93.

    Google Scholar 

  • Haroun, E. M., Hammond, J. A. &Sewell, M. M. H. (1980a). Resistance toFasciola hepatica in rats and rabbits following sensitising infection and treatment.Research in Veterinary Science,28, 377–379.

    Google Scholar 

  • Haroun, E. M., Hammond, J. A. &Sewell, M. M. H. (1980b). Resistance toFasciola hepatica in rats and rabbits following implantation of adult flukes contained in diffusion chambers.Research in Veterinary Science,29, 310–314.

    Google Scholar 

  • Haroun, E. M., Hammond, J. A. &Sewell, M. M. H. (1981). Passive transfer of humoral resistance toFasciola hepatica in rats and rabbits.Research in Veterinary Science,30, 309–311.

    Google Scholar 

  • Haroun, E. M., Hammond, J. A. &Sewell, M. M. H. (1982). Absorption of protective components from serum of cattle infected withFasciola hepatica.Research in Veterinary Science,33, 263–264.

    Google Scholar 

  • Harrison, L. J. S. (1978). Studies on the immunochemistry and serology ofTaenia saginata infection in cattle. Ph.D. Thesis, University of Edinburgh.

  • Harrison, L. J. S. (1981).Taenia saginata cysticercosis and sewage sludge disposal.Transactions of the Royal Society of Tropical Medicine and Hygiene,75, 893.

    Google Scholar 

  • Harrison, L. J. S. (1982). ELISA—used for the detection ofTaenia saginata metacestode infection in cattle.Current Topics in Veterinary Medicine and Animal Science,22, 47–51.

    Google Scholar 

  • Harrison, L. J. S. (1984). Surface and secreted antigens ofTaenia saginata.Annals of Tropical Medicine and Parasitology,78, 235.

    Google Scholar 

  • Harrison, L. J. S. (1991). Monoclonal antibodies and DNA probes in diagnosis. In:Proceedings of Biotechnology in Livestock in Developing Countries. (Ed. A.G. Hunter). Centre for Tropical Veterinary Medicine, The University of Edinburgh, pp. 252–271

  • Harrison, L. J. S. &Joshua, G. W. P. (1987). Immunoprophylaxis ofTaenia saginata cysticercosis. In:Helminth Zoonoses. Martinus Nijhoff, pp. 81–84.

  • Harrison, L. J. S. &Parkhouse, R. M. E. (1985). Antigens of taeniid cestodes of protection, diagnosis and escape.Current Topics in Microbiology and Immunology,120, 159–172.

    Google Scholar 

  • Harrison, L. J. S. &Parkhouse, R.M.E. (1986a). Passive protection againstTaenia saginata infection in cattle by a mouse monoclonal antibody reactive with the surface of the invasive oncospheres.Parasite Immunology,8, 319–332.

    Google Scholar 

  • Harrison, L. J. S. &Parkhouse, R. M. E. (1986b). Identification of protective antigens inTaenia saginata cysticercosis. Immunobiology and molecular biology of cestode infections. Coopers Animal Health Symposium, Melbourne. A2.

  • Harrison, L. J. S. &Parkhouse, R. M. E. (1989)Taenia saginata andTaenia solium—reciprocal models. Proceedings of the Symposium on Neurocysticercosis,Acta Leidensia,57, 143–152.

    Google Scholar 

  • Harrison, L. J. S. &Parkhouse, R. M. E. (1994). Antigens of parasitic helminths in protection and pathology. In:Helminthology. (Ed. Professor N. Chowdhury). Narosa Publishing House; distributed in Europe and North America by Springer Verlag, pp 258–271.

  • Harrison, L. J. S. &Sewell, M. M. H. (1980). The antigenic activity of chromatographic fractions of a saline extract ofTaenia saginata (Goeze, 1782) proglottides.Veterinary Immunology and Immunopathology,1, 361–369.

    Google Scholar 

  • Harrison, L. J. S. &Sewell, M. M. H. (1981a). A comparison of the enzyme-linked immunosorbent assay and the indirect haemagglutintion technique applied to sera from cattle experimentally infected withTaenia saginata (Goeze, 1782).Veterinary Immunopathology,2, 67–73.

    Google Scholar 

  • Harrison, L. J. S. &Sewell, M. M. H. (1981b). Antibody levels in cattle naturally infected withTaenia saginata metacestodes in Britain.Research in Veterinary Sciences,31, 62–64.

    Google Scholar 

  • Harrison, L. J. S. &Sewell, M. M. H. (1990). The zoonotic taeniae of Africa. In:Parasitic Helminths and Zoonoses in Africa. (Eds C. N. L. MacPherson and P. S. Craig). Unwin Hyman, London, pp 54–82.

    Google Scholar 

  • Harrison, L. J. S., Ortega-Pierres, G., Clark, N. W. T. &Parkhouse, R. M. E. (1982). Characterisation of larval cestode antigen. (In: Parasites—their world and ours).Molecular and Biochemical Parasitology, 55.

  • Harrison, L. J. S., Gallie, G. J. &Sewell, M. M. H. (1984a). Absorption of cysticerci in cattle after treatment withTaenia saginata cysticercosis with praziquantel.Research in Veterinary Science.37, 378–380.

    Google Scholar 

  • Harrison, L. J. S., Parkhouse, R. M. E. &Sewell, M. M. H. (1984b). Variation in “target” antigens between appropriate and inappropriate hosts ofTaenia saginata metacestodes.Parasitology,88, 659–663.

    Google Scholar 

  • Harrison, L. J. S., Le Riche, P. D. &Sewell, M. M. H. (1986). Variations inEchinococcus granulosus of bovine origin identified by enzyme electrophoresis.Tropical Animal Health and Production,18, 48–50.

    Google Scholar 

  • Harrison, L. J. S., Joshua, G. W. P., Wright, S. H. &Parkhouse, R. M. E. (1989). Specific detection of circulating surface/secreted glycoproteins of viable cysticerci inTaenia saginata cysticercosis.Parasite Immunology,11, 351–370.

    Google Scholar 

  • Harrison, L. J. S., Delgado, J. &Parkhouse, R. M. E. (1990). Differentiation ofTaenia saginata andTaenia solium by the use of cloned DNA fragments.Parasitology.100, 459–461.

    Google Scholar 

  • Harrison, L. J. S., Hughes, G., Nginyi, J. M., Ndegwa, E. W., Rugutt, M. K., Steele, G. M., Wright, S. H., Omundi, G., Malenya, G., Odera, G., Olum, J., Opicha, M. &Onyango-Abuje, J. A. (1993).Ante-mortem diagnosis and treatment forTaenia saginata cysticercosis. In:Progress Towards the Control of Helminthosis in Kenya. Proceedings NARP Helminthology Project Workshop, 24th and 25th February 1992. (Eds. J. A. Onyango-Abuge, R. K. Bain, S. W. Wanyangu and M. A. Ihiga) KARI, Nairobi, Kenya, pp 45–48.

    Google Scholar 

  • Hillyer, G. V., Galanes, M. S., Rodriguez-Perez, J., Bjorland, J., Lagrava, M. S., Guzman, S. R. &Bryan, R. T. (1992). Use of the FalconR assay screening test-enzyme-linked immunosorbent assay (FAST-ELISA) and the enzyme linked immunoelectrotransfer blot (EITB) to determine the prevaence of human fascioliasis in the Bolivian Altiplano.American Journal of Tropical Medicine and Hygiene,46, 603–609.

    Google Scholar 

  • Hughes, G., Hoque, M., Tewes, M. S., Wright, S. H. &Harrison, L. J. S. (1993). Sero-epidemiological study ofTaenia saginata cysticercosis in Swaziland.Research in Veterinary Science,55, 287–291.

    Google Scholar 

  • Hughes, G., Harrison, L. J. S. &Sewell, M. M. H. (1995). An investigation of the feasibility of using forecast models for the control of fasciolosis in the tropics and sub-tropics. ODA/NRRD Animal Health Programme Report.

  • Jeggo, M. H. &Sewell, M. M. H. (1977). Treatment of pre-patent equine strongyliasis.Veterinary Record,101, 187.

    Google Scholar 

  • Joshua, G. W. P., Harrison, L. J. S. &Sewell, M. M. H. (1988). Excreted/secreted products of developingTaenia saginata metacestodes.Parasitology,97, 477–487.

    Google Scholar 

  • Joshua, G. W. P., Harrison, L. J. S. &Sewell, M. M. H. (1989). Developmental changes in proteins and glycoproteins revealed by direct radio-labelling of viableTaenia saginata.Parasitology,99, 265–274.

    Google Scholar 

  • Joshua, G. W. P., Harrison, L. J. S. &Sewell, M. M. H. (1990). Cyst fluid protein antigens of developingTaenia saginata larvae.Parasitology,100, 463–467.

    Google Scholar 

  • Knobloch, J., Delgado, E., Alvarez, A., Reymann, V. &Biolek, R. (1985). Human fascioliasis in Cajamarca, Peru 1.—Diagnostic methods and treatment with praziquantel.Tropical Medicine and Parasitology,36, 88–90.

    Google Scholar 

  • Knobloch, J. (1985). Human fascioliasis in Cajamarca, Peru 2.—Humoral antibody response and antigenaemia.Tropical Medicine and Parasitology,36, 91–93.

    Google Scholar 

  • Kusiluka, L. J. M. (1995). Management systems and health problems of goats in Morogoro district Tanzania. M. Phil. Dissertation, University of Edinburgh.

  • Kusiluka, L. J. M., Kambarage, D. M., Mattewman, R. W., Daborn, C. J. &Harrison, L. J. S. (1995). Prevalence of ectoparasites of goats in Tanzania.Journal of Applied Animal Research,7, 69–74.

    Google Scholar 

  • Le Riche, P. D. &Sewell, M. M. H. (1977). Differentiation ofTaenia saginata andTaenia solium by enzyme electrophoresis.Transactions of the Royal Society of Tropical Medicine and Hygiene,71, 327–328.

    Google Scholar 

  • Le Riche, P. D. &Sewell, M. M. H. (1978a). Differentiation of taeniid cestodes by enzyme electrophoresis.International Journal for Parasitology,8, 479–483.

    Google Scholar 

  • Le Riche, P. D. &Sewell, M. M. H. (1978b). Identification ofEchnococcus granulosus strains by enzyme electrophoresis.Research in Veterinary Science,25, 247–248.

    Google Scholar 

  • Lehner, R. P. &Sewell, M. M. H. (1979a). Maintenancein vitro of adultFasciola hepatica in a continuous-flow system.Veterinary Parasitology,5, 315–323.

    Google Scholar 

  • Lehner, R. P. &Sewell, M. M. H. (1979b). Attempted immunisation of laboratory animals with metabolic antigens ofFasciola hepatica.Veterinary Science Communications,2, 337–340.

    Google Scholar 

  • Lloyd, S. (1984). Passive and active immunisation against cysticercosis. In: Some important parasitic infections in bovines considered from economic and social points of view. EU Publication. 187–198.

  • Lloyd, S., Soulsby, E. J. L. &Theodorides, V. J. (1978). Effect of albendazole on the metacestodes ofTaenia saginata in calves.Experimentia,34, 723–724.

    Google Scholar 

  • Mahato, S. N. (1984). Differentiation ofFasciola species and their intermediate hosts by enzyme electrophoresis. M.Sc. Dissertation, University of Edinburgh.

  • Mahato, S. N. (1993). Epidemiology and pathogenesis of fasciolosis in Eastern Nepal. Ph.D. Dissertation, University of Edinburgh.

  • Mahato, S. N., Harrison, L. J. S. &Hammond, J. A. (1992). Cloning of species specific and cross-reactive DNA probes fromFasciola hepatica andFasciola gigantica. Proceedings of the International Conference on Genetic Engineering and Biotechnology, Kathmandu, Nepal, April 15–19, 1991. (Reported by the same authors In:Transactions of the Royal Society of Tropical Medicine and Hygiene,88, 23).

  • Mahato, S. N., Harrison, L. J. S. &Hammond, J. A. (1993). Epidemiology of fasciolosis in Eastern Nepal. 14th International Conference of the World Association of the Advancement of Veterinary Parasitology, 8–13th August 1993. Cambridge, p 280. (Reported by same authors (1994) In:Transactions of the Royal Society of Tropical Medicine and Hygiene,88, 23).

  • Mahato, S. N., Hammond, J. A. &Harrison, L. J. S. (1994a). Laboratory based experiment on the ability ofLymnaea auricularia race rufescens andLymnaea viridis to survive in drought conditions.Veterinary Review,10, 10–12.

    Google Scholar 

  • Mahato, S. N., Harrison, L. J. S. &Hammond, J. A. (1994b). Pathogenesis ofFasciola gigantica in buffaloes in Eastern Nepal.Transactions of the Royal Society of Tropical Medicine and Hygiene,88, 23.

    Google Scholar 

  • Mahato, S. N., Harrison, L. J. S. &Hammond, J. A. (1994c). Efficacy of Triclabendazole againstFasciola gigantica in buffaloes in Eastern Nepal.Veterinary Record,135, 579–580.

    Google Scholar 

  • Mahato, S. N., Harrison, L. J. S. &Hammond, J. A. (1995). Bacillary haemoglobinuria in a buffalo calf: a case report.Veterinary Review,9, 36–38.

    Google Scholar 

  • Maurice, J. (1994). Is something lurking in your liver?New Scientist. March 26–31.

  • Ndamukong, K. J. N. &Sewell, M. M. H. (1992). Resistance to benzimidazole anthelmintics by trichostrongyles in sheep and goats in North-West Cameroon.Veterinary Parasitology,41, 335–339.

    Google Scholar 

  • Ndamukong, K. J. N., Asanji, N. F. &Sewell, M. M. H. (1987). Productivity in sheep and goats under three management systems at Bamenda, Cameroon.Tropical Animal Health and Production,19, 237–244.

    Google Scholar 

  • Ndamukong, K. J. N., Asanji, N. F. &Sewell, M. M. H. (1989). Mortality and disease in small ruminants in the North West Province of Cameroon.Tropical Animal Health and Production,21, 191–196.

    Google Scholar 

  • Nginyi, J. M., Onyango-Abuje, J. A. &Harrison, L. J. S. (1993). Diagnosis ofStilesia hepatica infection in sheep.Tropical Animal Health and Production,25, 225–227.

    Google Scholar 

  • Nyanzunda, T. M. (1993). A Western blot study ofFasciola gigantica antigen recognition patterns in cattle. M.Sc. Dissertation, University of Edinburgh.

  • Onyango-Abuje, J. A., Nginyi, J., Rugutt, M. K., Wright, S. H., Lumbumba, P. Hughes, G. &Harrison, L. J. S. (1995a). Sero-epidemiological survey ofTaenia saginata cysticercosis in Kenya.Veterinary Parasitology, (in press).

  • Onyango-Abuje, J. A., Hughes, G., Opicha, M., Nginyi, J., Rugutt, M. K., Wright, S. H. &Harrison, L. J. S. (1995b). Diagnosis ofTaenia saginata cysticercosis in Kenyan cattle by antibody and antigen ELISA.Veterinary Parasitology, (in press).

  • Parkhouse, R. M. E. &Harrison, L. J. S. (1987). Cyst fluid and surface associate glycoprotein antigens ofTaenia spp. metacestodes.Parasite Immunology,9, 263–268.

    Google Scholar 

  • Parkhouse, R. M. E. &Harrison, L. J. S. (1989). Antigens of parasitic helminths in diagnosis, protection and pathology. A symposium of the British Society of Parasitology and the Linnean Society, Research developments in the study of parasitic infections.Parasitology,99, S5-S16.

    Google Scholar 

  • Parkhouse, R. M. E., Harrison, L. J. S., Ortega-Pierres, G. &Clark, N. W. T. (1984). Diagnostic antigens for bovine and human cysticercosis.Annals of Tropical Medicine and Parasitology,78, 235.

    Google Scholar 

  • Pullan, N. B. &Sewell, M. M. H. (1980). Parasitic gastro-enteritis in calves on the Jos Plateau, Nigeria.Tropical Animal Health and Production,12, 203–208.

    Google Scholar 

  • Pullan, N. B., Sewell, M. M. H. &Hammond, J. A. (1970). Studies on the pathogenicity of massive infections ofFasciola hepatica L in lambs.British Veterinary Journal,126, 543–558.

    Google Scholar 

  • Purvis, G. M. &Sewell, M. M. H. (1971). The host parasite relationship between the domestic rabbit andTrichostrongylus colubriformis.Veterinary Record,89, 151.

    Google Scholar 

  • Purvis, G. M. &Sewell, M. M. H. (1972a).Trichostrongylus colubriformis: age resistance in the rabbit,Oryctolagus cuniculus.Experimental Parasitology,32, 191–195.

    Google Scholar 

  • Purvis, G. M. &Sewell, M. M. H. (1972b). Eosinophilia and basophilia associated with self-cure in rabbits infected withTrichostrongylus colubriformis.Veterinary Record,90, 399–400.

    Google Scholar 

  • Rajapaksa, G. R. (1989). The effect of exercise on the blood parameters ofFasciola hepatica infected ruminants. M.Sc. Dissertation, University of Edinburgh.

  • Rickard, M. D. &Brumley, J. L. (1981). Immunisation of calves againstTaenia saginata infection using antigens collected byin vitro incubation ofT. saginata oncospheres or ultrasonic disruption ofT. saginata andT. hydatigena oncospheres.Research in Veterinary Science,30, 99–103.

    Google Scholar 

  • Rickard, M. D., Harrison, G. B. L., Heath, D. D. &Lightowlers, M.A. (1995).Taenia ovis vaccine —Quo Vadit.Parasitology,110, S5-S9.

    Google Scholar 

  • Rodriguez-del Rosal, D., Correa, D. &Flisser, A. (1989). Swine cysticercosis: detection of parasite products in serum.Veterinary Record,124, 488.

    Google Scholar 

  • Sewell, M. M. H. (1966). The pathogenesis of fascioliasis.Veterinary Record,78, 98–105.

    Google Scholar 

  • Sewell, M. M. H. (1967a) Serum enzyme activities in acute ovine fascioliasis.Veterinary Record,80, 577–578.

    Google Scholar 

  • Sewell, M. M. H. (1967b). The aetiology of anaemia in chronic fascioliasis; experiments with radioactive tracers.Veterinary Record,80, 579–580.

    Google Scholar 

  • Sewell, M. M. H. (1973). The influence of anthelmintic treatment of ewes on the relative proportions of gastro-intestinal nematode parasites in their lambs.Veterinary Record,92, 371–372.

    Google Scholar 

  • Sewell, M. M. H. &Gallie, G. J. (1971). Experimental cysticercosis of cattle.Proceeding of the XXIX World Veterinary Congress, Mexico City, 897–900.

  • Sewell, M. M. H. &Gallie, G. J. (1974) Immunological studies on experimental infections with the larval stage ofTaenia saginata. In:Parasitic Zoonoses Clinical and Experimental Studies. Academic Press, New York, pp 187–199.

    Google Scholar 

  • Sewell, M. M. H. &Gallie, G.J. (1975). Experimental studies onTaenia saginata infections in cattle.Parasitology,71, xiii-xiv.

    Google Scholar 

  • Sewell, M. M. H. &Hammond, J. A. (1972). The detection ofFasciola eggs in faeces.Veterinary Record,90, 510–511.

    Google Scholar 

  • Sewell, M. M. H. &Harrison, L. J. S. (1978a). Bovine cysticerocsis.The Veterinary Record,102, 223.

    Google Scholar 

  • Sewell, M. M. H. &Harrison, L. J. S. (1978b). Predilection sites for bovine cysticercosis.The Veterinary Record,103, 18–19.

    Google Scholar 

  • Sewell, M. M. H., Hammond, J. A. &Dinning, D. C. (1968). Studies on the aetiology of anaemia in chronic fascioliasis in sheep.British Veterinary Journal,124, 160–170.

    Google Scholar 

  • Stevenson, P., Holmes, P. W. &Muturi, J. M. (1981). Effect of albendazole onTaenia saginata cysticerci in naturally infected cattle.Veterinary Record,109, 82.

    Google Scholar 

  • Trawford, A. F. (1988). Techniques for the differentiation ofFasciola species. M.Sc. Dissertation, University of Edinburgh.

  • Walther, M. &Bhogal, M. S. (1983). Experimental chemotherapy ofTaenia saginata cysticercosis - a field trial.Tropenmedizin und Parasitologia.34, 263–266.

    Google Scholar 

  • Wamae, L. W., Ndegwa, E. W., Malenya, G. M., Harrison, L. J. S., Hammond, J. A., Oolum, J., Odera, G., Omundi, G. &Onyango-Abuje, J. A. (1993).Fasciola gigantica studies. In:Progress Towards the Control of Helminthosis in Kenya. Proceedings NARP Helminthology Project Workshop, 24th and 25th February 1992. (Eds. J. A. Onyango-Abuge, R. K. Bain, S. W. Wanyangu and M. A. Ihiga). Kari, Nairobi, Kenya, pp. 54–56.

    Google Scholar 

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  1. Centre for Tropical Veterinary Medicine, Easter Bush, University of Edinburgh, EH25 9RG, Roslin, Midlothian, Scotland

    L. J. S. Harrison, J. A. Hammond & M. M. H. Sewell

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Harrison, L.J.S., Hammond, J.A. & Sewell, M.M.H. Studies on helminthosis at the centre for tropical veterinary medicine (CTVM). Trop Anim Health Prod 28, 23–39 (1996). https://doi.org/10.1007/BF02250725

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