Abstract
A new approach for the stabilization of phospholipase C by conjugation with a proteinase inhibitor is proposed. A heat-stable fraction obtained from a conjugate retained its initial activity for an hour at an incubation temperature of 50°C. An appropriate method of conjugation using an affinity adsorbent preventing the appearance of inactive forms of the conjugate has been developed.
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Additional information
Mirzo Ulugbek Tashkent State University, fax (3712) 46 24 72. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 115–117, January–February, 1998.
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Sof'ina, E.Y., Rakhimov, M.M. Stabilization of phospholipase C fromClostridium perfringens by conjugation with a trypsin inhibitor. Chem Nat Compd 34, 89–91 (1998). https://doi.org/10.1007/BF02249695
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DOI: https://doi.org/10.1007/BF02249695