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Immobilization of synthetic glycopeptides on polymeric supports

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Abstract

The synthesis of the 6-aminohexyl β-glycoside of O-(N-acetylglucosaminyl)-(β1→4)-MDP (GMDP) is described. Conjugates with polyacrylamide, including lipophilic conjugates (containing phosphatidylethanolamine residues) and biotinylated polymeric probes with MDP specificity have been obtained on the basis of ω-spacered glycopeptides. Conjugates of MDP with dextran have also been synthesized.

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Authors
  1. A. E. Zemlyakov
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Simferopol' State University, 4 Yaltinskaya ul., Simferopol', Crimea, Ukraine. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 104–111, January–February, 1998.

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Zemlyakov, A.E. Immobilization of synthetic glycopeptides on polymeric supports. Chem Nat Compd 34, 80–85 (1998). https://doi.org/10.1007/BF02249693

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  • DOI: https://doi.org/10.1007/BF02249693

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