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Chemistry of Natural Compounds

, Volume 34, Issue 1, pp 15–28 | Cite as

Presynaptic and postsynaptic neurotoxins. Investigation of the structures of the immune recognition sections

  • B. Z. Dolimbek
  • M. Z. Atassi
  • Sh. I. Salikhov
Article

Abstract

This paper discusses literature reports over the last 12 years and the results of our own experimental investigations of the structures of the immune recognition regions of protein antigens — in particular presynaptic and postsynaptic neurotoxins from spider and snake venoms.

Keywords

Organic Chemistry Experimental Investigation Literature Report Protein Antigen Snake Venom 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

ACR

acetylcholine receptor

LT

α-latrotoxin

NT II

neurotoxin II

BTX

α-bungarotoxin

BSA

bovine serum albumin

PBS

0.15 M NaCl in 0.01 M phosphate buffer, pH 7.2

PI

protection index: the ratio of LD50 for BTX to LD50 for a control

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Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • B. Z. Dolimbek
    • 1
  • M. Z. Atassi
    • 2
  • Sh. I. Salikhov
    • 1
  1. 1.A. S. Sadykov Institute of Bioorganic ChemistryAcademy of Sciences of the Republic of UzbekistanTashkent
  2. 2.Baylor College of Medicine, One Baylor PlazaHoustonUSA

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