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An unusual clinical manifestation of secondary Sjögren's syndrome and concomitant Paterson-Kelly syndrome


We describe the case of a female patient who presented with rheumatoid arthritis accompanied by severe dysphagia that led to prostration. The clinical picture and a barium contrast swallowing study suggested neoplastic proliferation at the borderline between the hypopharynx and the oesophagus. A comprehensive examination, however, did not confirm neoplasm. Dysphagia was caused rather by mucoso-fibrotic changes at the borderline between the hypopharynx and the oesophagus, representing the simultaneous presence of the Paterson-Kelly syndrome and secondary Sjögren's syndrome.

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  1. Flusser, J. Plummer-Vinson's syndrome. In: Repetitorium, 4th ed., Ed.: Štrok et al. Avicenum, Praha, 1982, 1393–1394.

    Google Scholar 

  2. Foster, H. Association of DR 3 with susceptibility to and severity of primary Sjögren's syndrome in a family study. Br J Rheumatol 1992, 31, 309–314.

    PubMed  Google Scholar 

  3. Fox, R. Sjögren's syndrome. Proposed criteria for classification. Arthritis Rheumatol 1986, 29, 577–585.

    Google Scholar 

  4. Kraus, A. et al. Raynaud's phenomenon in primary SS. Association with other extraglandular manifestations. J Rheumatol 1992, 19, 1527–1534.

    PubMed  Google Scholar 

  5. Markusse, H.M. Ophthalmological examinations of patients with primary Sjögren's syndrome selected from rheumatological practice. Br J Rheumatol 1992, 31, 473–476.

    PubMed  Google Scholar 

  6. Markusse, H.M. The diagnostic value of salivary fluid levels of beta 2 mikroglobulin, lysozyme and lactoferrin for primary Sjögren's syndrome. Clinical Rheumatol 1992, 11, 521–525.

    Google Scholar 

  7. Markusse H.K. et al. Glands in primary digital substraction sialography of the parotid glands in primary SS. J Rheumatol 1993, 20, 279–283.

    PubMed  Google Scholar 

  8. Oxholm, P. Primary Sjögren's syndrome-clinical and laboratory markers of disease activity. Semin Arthritis Rheum 1992, 22, 114–126.

    Article  PubMed  Google Scholar 

  9. Pavelka, K. Sjögren's syndrome. Fysiatr Věstn 1990, 68, 22–31.

    Google Scholar 

  10. Vencovský, J. Criteria for classification of Sjögren's syndrome. Fysiatr Věstn 1992, 70, 126–131.

    Google Scholar 

  11. Whaley, K., Alspaugh, M.A. Sjögren's syndrome. In: Textbook of Rheumatology, 3rd ed., Ed.: Kelly, W.N. et al., Philadelphia, W.B. Saunder's Company 1989, 999–1019.

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Dejmkova, H., Pavelka, K. An unusual clinical manifestation of secondary Sjögren's syndrome and concomitant Paterson-Kelly syndrome. Clin Rheumatol 13, 305–308 (1994).

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