Summary
A 59-year-old patient suffering from hyperlipidaemia developed a chronic vitamin A intoxication syndrome after ingestion of 30000 IE retinol/daily over a period of six years. Functional disability of the right hip was caused by radiologically documented hyperostosis of the acetabular circumference. Finally, a prosthesis had to be implanted because of rapid destructive osteoarthritis of the right hip. Implications of vitamin A for rheumatological management are discussed.
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Theiler, R., Hanck, A., Schreiber, A. et al. Reduced vitamin a tolerance in a hyperlipidaemia patient with rapid destructive and hyperostotic osteoarthritis of the hip. Clin Rheumatol 13, 293–298 (1994). https://doi.org/10.1007/BF02249030
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DOI: https://doi.org/10.1007/BF02249030