Psychopharmacology

, Volume 116, Issue 1, pp 117–119 | Cite as

Nicotine may relieve symptoms of Parkinson's disease

  • Karl Olov Fagerström
  • Ovide Pomerleau
  • Bruno Giordani
  • Fred Stelson
Rapid Communications

Abstract

Two elderly patients with Parkinson's disease were treated with nicotine gum and patch. Reliable changes in symptomatology were noted, using a single-subject, placebo-control reversal design. Improvement was associated with active nicotine dosing and involved diminished tremor and disorganized thinking in one patient and diminished bradykinesia and increased energy in the other.

Key words

Parkinson's disease Treatment Nicotine patch Nicotine gum 

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References

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Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • Karl Olov Fagerström
    • 1
  • Ovide Pomerleau
    • 2
  • Bruno Giordani
    • 2
  • Fred Stelson
    • 2
  1. 1.Pharmacia Research LaboratoriesHelsingborgSweden
  2. 2.Medical CenterUniversity of MichiganAnn ArborUSA

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